BACKGROUND Carcinogenic human papillomaviruses (HPVs) cause a large proportion of anal cancers. Human immunodeficiency virus (HIV)-infected men who have sex with men (MSM) are at increased risk of HPV infection and anal cancer compared with HIV-negative men. We evaluated risk factors for HPV infection and anal precancer in a population of HIV-infected MSM. METHODS Our study included 305 MSM a...

ln 1969, the International Agency for Research on Cancer (IARC) initiated a programme to evaluate the carcinogenic risk of chemicals to humans and to produce monographs on individual chemicals. The Monographs programme has since been expanded to include consideration of exposures to complex mixtures of chemicals (which occur, for example, in some occupations and as a result of human habits) and...

Studies have been carried out on the nature of the proteins of mouse skin to which hydrocarbons are bound after topical application. No relation was found between the carcinogenic activities of various hydrocarbons and their inhibition of the incorporation of DL-lysine-2-C 1~ into mouse skin proteins. Salt fractionation of the proteins to which 1,~,5,6-dibenzanthracene-9,10-C TM is bound reveal...

The current investigation aimed to examine the present status of pollution in Bhima River using indices (degree contamination, heavy metal evaluation index, & index) and health risk assessment (non-carcinogenic carcinogenic) by choosing some metals like copper (Cu), chromium (Cr), manganese (Mn), cadmium (Cd), nickel (Ni), lead (Pb), zinc (Zn). Eight samples surface water were collected mon...

Several metals such as arsenic, beryllium, chromium and nickel are carcinogenic to man when they occur in certain well-defined physicochemical forms. The carcinogenic potential of these metals is linked to their mutagenic properties. The determination of the metal or possibly of its metabolites in biological media and the cytogenetic examination of somatic cells are two methods that can current...

In 1969, the International Agency for Research on Cancer (IARC) initiated a programme to evaluate the carcinogenic risk of chemicals to humans and to produce monographs on individual chemicals. The Monographs programme has since been expanded to include consideration of exposures to complex mixtures of chemicals (which occur, for example, in some occupations and as a result of human habits) and...

ln 1969, the International Agency for Research on Cancer (lARe) initiated a programme to evaluate the carcinogenic risk of chemicals to humans and to produce monographs on individual chemicals. The Monographs programme has since been expanded to incIude consideration of exposures to complex mixtures of chemicals (which occur, for example, in some occupations and as a result of human habits) and...

ln 1969, the International Agency for Research on Cancer (lARC) initiated a programme to evaluate the carcinogenic risk of chemicals to humans and to produce monographs on individual chemicals. The Monographs programme has since been expanded to include consideration of exposures to complex mixtures of chemicals (which occur, for example, in some occupations and as a result of human habits) and...

Risk assessment models strive to predict risks to humans from toxic agents. Safety factors and assumptions are incorporated into these models to allow a margin of error. In the case of cancer, substantial evidence shows that the carcinogenic process is a multistage process driven by the interaction of exogenous carcinogenic exposures, genetic traits, and other endogenous factors. Current risk a...