نتایج جستجو برای: carcinoembryonic antigen

تعداد نتایج: 200263  

2006
M. Garcia C. Seigner C. Bastid R. Choux M. J. Payan H. Reggio

Carcinoembryonic antigen, an apical membrane glycoprotein expressed in normal human colonie epithelial cells, colonie polyps, tumor, and tissue culture cell lines originating from colonie adenocarcinomas, is generally considered to have a molecular weight of 180,000. Using sodium dodecyl sulfate-polyacrylamide gel electrophoresis associated with immunoprecipitation or immunoblotting with both m...

2012
Markus Chmielewski Amit Maliar Zelig Eshhar Hinrich Abken

Despite intensive treatment, pancreatic adenocarcinoma still has the worst prognosis among all malignancies. Using clinically relevant models, we demonstrated the therapeutic efficacy of adoptively transferred T cells engineered with a carcinoembryonic antigen (CEA)- and ERBB2-specific chimeric antigen receptor against pancreatic carcinoma. Targeting CD24, a putative cancer stem cell antigen ex...

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