The metabolism of benzoate, cyclohex-1-ene carboxylate, and cyclohexane carboxylate by "Syntrophus aciditrophicus" in cocultures with hydrogen-using microorganisms was studied. Cyclohexane carboxylate, cyclohex-1-ene carboxylate, pimelate, and glutarate (or their coenzyme A [CoA] derivatives) transiently accumulated during growth with benzoate. Identification was based on comparison of retentio...

ABSTRACT The coordination polymer [Ti(OiPr)3(OOCCH2CH2CH2C3N2H3)] n was prepared from 4-(imidazol-1-yl)butyric acid and titanium isopropoxide. The structure of the compound is remarkable, as the carboxylate group is coordinated in a chelating manner and no dimerization of the Ti(OiPr)3 groups through OR bridges was observed. GRAPHICAL ABSTRACT

The Sn atom in the title compound, [Sn(C(7)H(6)Cl)(3)(C(8)H(14)NO(2)S(2))], is coordinated by three chlorobenzyl ligands and one carboxylate O atom of the substituted acetate ligand in a distorted tetra-hedral environment. Three of the C atoms of the n-butyl group are disordered over two sites with equal occupancies.

The title compound, C12H18N4O2, crystallizes in the zwitterionic form with protonation at the N atom of the piperazine ring bearing the carboxylate group. The piperazine ring adopts a slightly distorted chair conformation. In the crystal, N-H⋯O hydrogen bonds are observed, forming chains along [010]. The packing is consolidated by C-H⋯O inter-actions, which generate a three-dimensional network.

Although uncharged structures analogous to the carboxyl group of the amino acid molecule have served in place of that group for transport into some cells, we find that substitution either by the carboxamide group or by the chloromethyl ketone group eliminates inhibition of transport Systems A or L of the Ehrlich ascites tumor cell. Comparison of the loss of System L transport on acidification s...

New functional monomers bearing a methacrylate, a bisphosphonate function and, for most, an internal carboxylate group, were prepared for incorporation into copolymers with adhesive or anticorrosive properties. Methanolysis of some trimethylsilyl bisphosphonate esters not only deprotects the desired bisphosphonate function but also regioselectively cleaves the alkyl ester function without affec...

1 The binding of a series of amide derivatives of methotrexate to Lactobacillus casei dihydrofolate reductase has been studied by inhibition constant measurements and by 'H n.m.r. spectroscopy. 2 Amide modification of the a-carboxylate of methotrexate was found to prevent interaction of the y-carboxylate with the imidazole of His 28. 3 Estimates of the contributions to the binding energy from t...

Biosynthetic studies with (13)C-labelled acetates and methionine revealed that the infamous, food-related toxin bongkrekic acid from Burkholderia gladioli is a polyketide with acetate-derived beta-branches and a carboxylate terminus derived from the methyl group of an acetate.

A shape auxiliary approach for the synthesis of shape-controlled gold nanocrystals with functional moieties is established; carboxylate-functionalized gold polyhedra were successfully synthesized in a one-pot reaction in the presence of poly(dimethylaminoethyl methacrylate), which contains the dimethylaminoethyl group as a shape auxiliary.