نتایج جستجو برای: caprolactone scaffold

تعداد نتایج: 26001  

Journal: :International journal of biological macromolecules 2015
Vuyiswa Mkhabela Suprakas Sinha Ray

A new type of hybrid three-dimensional scaffolds was prepared using poly(ɛ-caprolactone) (PCL) and chitosan-modified montmorillonite by solvent casting and particulate leaching method. The scaffolds were characterized by scanning electron microscopy coupled with energy dispersive spectroscopy (EDS), X-ray diffraction (XRD), and dynamic mechanical analysis to study the structural and mechanical ...

2016
Sascha Zaiss Toby D. Brown Johannes C. Reichert Arne Berner

Melt electrospinning is a promising approach to manufacture biocompatible scaffolds for tissue engineering. In this study, melt electrospinning of poly(ε-caprolactone) onto structured, metallic collectors resulted in scaffolds with an average pore size of 250-300 μm and an average fibre diameter of 15 μm. Scaffolds were seeded with ovine osteoblasts in vitro. Cell proliferation and deposition o...

Journal: :Biomaterials 2010
Ferry P W Melchels Katia Bertoldi Ruggero Gabbrielli Aldrik H Velders Jan Feijen Dirk W Grijpma

The technologies employed for the preparation of conventional tissue engineering scaffolds restrict the materials choice and the extent to which the architecture can be designed. Here we show the versatility of stereolithography with respect to materials and freedom of design. Porous scaffolds are designed with computer software and built with either a poly(D,L-lactide)-based resin or a poly(D,...

2016
Sasima Puwanun Frazer J. Bye Sheila MacNeil Gwendolen C. Reilly Nicola H. Green Jianxun Ding

Composite tissue-engineered constructs combining bone and soft tissue have applications in regenerative medicine, particularly dentistry. This study generated a tri-layer, electrospun, poly-ε-caprolactone membrane, with two microfiber layers separated by a layer of nanofibers, for the spatially segregated culture of mesenchymal progenitor cells (MPCs) and fibroblasts. The two cell types were se...

Journal: :Interface focus 2014
Valeria Chiono Pamela Mozetic Monica Boffito Susanna Sartori Emilia Gioffredi Antonella Silvestri Alberto Rainer Sara Maria Giannitelli Marcella Trombetta Daria Nurzynska Franca Di Meglio Clotilde Castaldo Rita Miraglia Stefania Montagnani Gianluca Ciardelli

Bi-layered scaffolds with a 0°/90° lay-down pattern were prepared by melt-extrusion additive manufacturing (AM) using a poly(ester urethane) (PU) synthesized from poly(ε-caprolactone) diol, 1,4-butandiisocyanate and l-lysine ethyl ester dihydrochloride chain extender. Rheological analysis and differential scanning calorimetry of the starting material showed that compression moulded PU films wer...

Journal: :Chemical and Biochemical Engineering Quarterly 2021

Natural polymer-based scaffolds are generally considered as favourable matrices for <br /> the adhesion and growth of cells in tissue repair. One most popular materials this respect is silk fibroin, known its wide usage biomedical applications. This work focuses on development electrospun based poly(ε-caprolactone) (PCL) fibroin (SF) evaluated regarding SF effect their morphology, surface...

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