Tracy M Frech1*, Brian Breviu2, Jessica T Zhu3 and Lesley Saketkoo4 1University of Utah Department of Internal Medicine, Division of Rheumatology and Salt Lake City Veterans Affair Medical Center, USA 2University of Utah Department of Internal Medicine and Salt Lake City Veterans Affair Medical Center, USA 3Undergraduate Boston College, Biology B.S., USA 4Louisiana State University Health Scien...

OBJECTIVE The aim of this study was to evaluate "in vivo" the oral microcirculatory characteristics in patients with oral lichen planus (OLP) and to discover any differences in microcirculation in comparison with healthy patients. STUDY DESIGN Twenty patients with established diagnosis of OLP and 20 healthy patients were examined in our laboratory by means of contact optical probe videocapill...

Nailfold capillaroscopy (NC) is a non-invasive imaging technique employed to assess the condition of blood capillaries in the nailfold and is particularly useful for diagnosis of scleroderma spectrum disorders and Raynaud’s phenomenon. Diagnosis is based on the identification of particular scleroderma patterns in the images which are typically grouped into early, active and late patterns. In th...

Raynauds phenomena (RP) is a commonly encountered clinical manifestation which may be primary or secondary to underlying disease. There is imbalance between vasoconstricting and vasodilating factors. Physical examination, nailfold capillaroscopy and immunological tests can differentiate primary from secondary RP. Treatment involves prevention of RP so that permanent ischemic damage i.e. gangren...

A software application is presented, for the detection and measurement of capillaries in images of capillaroscopy. This software is comprised by a measurement module and a Graphical User Interface module. The measurement module segments capillaries in the input image. The user interface provides methods for the automatic and interactive measurement of capillaries at regions of interest. In addi...