نتایج جستجو برای: candida parapsilosis
تعداد نتایج: 30055 فیلتر نتایج به سال:
Candida parapsilosis is emerging as a potential pathogen for onychomycosis. A 4-year-old male child with perimembranous ventricular septal defect (VSD) was admitted with features of cystitis and was treated with broad spectrum antibiotics. Two weeks later, he developed yellowish discoloration of nails of both hands. The sloughed out nail, on microscopy, showed numerous yeast forms that were ide...
Oral candidosis is a common problem in immunocompromised patients, and whilst Candida albicans is regarded as the principal cause of infection, other non-Candida albicans Candida (NCAC) species are increasingly being recognized as human pathogens. Relatively little is known about the virulence factors associated with NCAC species, and the aim of this study was to use a reconstituted human oral ...
Inteins are coding sequences that are transcribed and translated with flanking sequences and then are excised by an autocatalytic process. There are two types of inteins in fungi, mini-inteins and full-length inteins, both of which present a splicing domain containing well-conserved amino acid sequences. Full-length inteins also present a homing endonuclease domain that makes the intein a mobil...
UNLABELLED Disseminated fungal infections are still rare conditions, mostly caused by Candida spp. during immunosuppression. Infection of immunocompetent individuals is uncommon. Endocarditis is a rare manifestation during candidaemia, mostly in patients with prosthetic valves. Affection of previously unaltered valves is uncommon. CASE PRESENTATION We presented a case of a young, previously h...
Historically, Candida species represented a catch-all taxonomic grouping for yeasts that exhibited hyphal or pseudohyphal branching and did not form sexual spores. However, with the advent of molecular typing of DNA sequences, it is now apparent that Candida represent a diverse range of species within the Hemiascomycetes, which also includes the model yeast Saccharomyces cerevisiae. Several Can...
Currently, it is accepted that there are three species that were formerly grouped under Candida parapsilosis: C. para- psilosis sensu stricto, Candida orthopsilosis, and Candida metapsilosis. In fact, the antifungal susceptibility profiles and distinct virulence attributes demonstrate the differences in these nosocomial pathogens. An accurate, fast, and economical identification of fungal speci...
Previous pharmacodynamic studies using in vivo candidiasis models have demonstrated that the 24-h area under the concentration-time curve (AUC)/MIC is a good descriptor of the echinocandin exposure-response relationship. Further studies investigating the 24-h AUC/MIC target for a stasis endpoint identified free-drug 24-h AUC/MIC against Candida albicans and were similar for two echinocandins, a...
OBJECTIVES The objectives of this study were to determine species distribution and in vitro antifungal susceptibility of Candida isolates identified in the multicentre China-SCAN study of invasive Candida infection (ICI) in intensive care units (ICUs) across China. METHODS Candida isolates from patients in the China-SCAN study with documented ICI were evaluated by a central laboratory. Specie...
Antimycotic perfusion through Candida biofilms was demonstrated by a modification of a simple in vitro diffusion cell bioassay system. Using this model, the perfusion of three commonly used antifungal agents, amphotericin B, fluconazole, and flucytosine, was investigated in biofilms of three different Candida species (i.e., Candida albicans, Candida parapsilosis, and Candida krusei) that were d...
24 Two new cryptic sister species, Candida orthopsilosis and Candida metapsilosis were 25 recently identified by consistent DNA sequence differences among several genes within 26 the genetically heterogeneous Candida parapsilosis complex. Here, we present data 27 demonstrating that Pyrosequencing analysis of 20 nucleotides of the Internal Transcribed 28 Spacer Region 2 rapidly and robustly dist...
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