OBJECTIVE To evaluate Candida parapsilosis candidaemia in a neonatal unit over 7 years. DESIGN Case series study. SETTING A 2000-bed tertiary-care university hospital at São Paulo, Brazil. PARTICIPANTS Neonates hospitalised in a 63-bed neonatal unit. PRIMARY AND SECONDARY OUTCOME MEASURES We evaluated the incidence of C parapsilosis fungemia in a neonatal unit from 2002 through 2008 and...

background: candida parapsilosis is an emergent agent of invasive fungal infections. this yeast is one of the five most widespread yeasts concerned in invasive candidiasis. c. parapsilosis stands out as the second most common yeast species isolated from patients with bloodstream infections especially in neonates with catheter. recently several reports suggested that its reduced susceptibility t...

We compared the in vivo efficacy of single large dose of caspofungin to that of daily smaller caspofungin doses (with same cumulative doses) against C. albicans (echinocandin susceptible and resistant isolates) and the “psilosis� group in a neutropenic murine model. Seven treatment groups were formed for C. orthopsilosis, C. metapsilosis and C. albicans (no treatment, 1, 2 and 3 mg/kg caspo...

chromagar candida is a new chromogenic culture medium that is used for the isolation and direct identification of some of the most clinically important yeast pathogens on the basis of colony colour. the aim of the study was to isolate and identify candida species from the oral cavity with chromagar candida. samples (158) from 68 orthodontic patients wearing upper removable orthodontic appliance...

With the advent of next-generation sequencing and microbial community characterization, we are beginning to understand the key factors that shape early-life microbial colonization and associated health outcomes. Studies characterizing infant microbial colonization have focused mostly on bacteria in the microbiome and have largely neglected fungi (the mycobiome), despite their relevance to mucos...

Editorial In many diagnostic microbiology laboratories the species identification process starting from cultured colonies has recently undergone some significant changes. Where not long ago car-bon/nitrogen source utilization tests in the form of colorful tubes or well-based devices down to chip card size dominated the field, we now find a purely biophysical instrument, a MALDI-ToF mass spectro...

background recent evidences have revealed that in more than 65% of microbial infections, biofilms have critical roles. the ability of yeasts to form biofilms on surface of medical devices such as urine catheters is an important reason of the capability of these microorganisms to cause human disease. objectives the aim of this study was to isolate and identify yeasts on the surfaces of urine cat...

background and purpose: candida species are the most opportunistic fungi affecting the nails and resulting in onychomycosis. in this study, we identified and evaluated in-vitro susceptibility of the recovered isolates against fluconazole (flc), voriconazole (vrc), and clotrimazole (clt) using the clinical and laboratory standards institute (clsi) m27-a3 document. materials and methods: from pat...