The concept of Cancer Unknown Primary (CUP) has evolved with the advent medical oncology. CUP can be difficult to diagnose and represents 2 5% new cancers, therefore not exceptionally rare. Within CUPs identified a subset favourable prognosis tumours, however vast majority patients belongs poor group.CUP features significant oncological challenges, such as unravelling biological transversal iss...

BACKGROUND The OPENMinds Primary Care group is a group of European primary care physicians (PCPs) with an interest in pain management, formed to improve the understanding and management of chronic pain in primary care. OBJECTIVE A survey was conducted to assess the challenges of chronic nonmalignant pain (CNMP) management in primary care in Europe, focusing particularly on pain assessment, op...