Introduction:Oral Squamous Cell Carcinoma (OSCC) is an invasive neoplasm with a high prevalence. Matrix Metalloproteinase (MMP) has been thought to play an important role in both the invasion and metastasis of tumors. The aim of this study was to explore the significance of MMPs expression in clinical outcome of these patients. Materials:The most recognized data Bases such as PubMed, Google sc...

objectives: epithelial-mesenchymal transition (emt) is a fundamental stage in cancer metastasis and the presence of vascular invasion is a strong indication of the spread of the malignant tumor cells. regulation of the emt is a complex process in which several different transcription factors are involved. eomesodermin (eomes) as a member of the t-box gene family is an important component in the...

results of the 53 neck dissection specimens, histopathology showed metastases in 16 cases. the overall accuracy of usgfna, us and palpation was 96%, 68% and 70%, respectively. the specificity of usgfna was superior to palpation and us alone. usgfna had the highest sensitivity, predictive value and accuracy in detecting cervical metastases compared with other performed tests. conclusion in our s...

Breast metastasis of ovarian carcinoma is rare. To date, only 39 cases have been reported in the English-language  literature  so  far.  We  are  herewith  reporting  a  primary  ovarian  papillary  serous  cyst adenocarcinoma metastasing to breast and epsilateral supraclavicular node in a 58 year old female as the first case in our centre, located at North-East India.  The purpose of reporting...

background and objective: oral cancer accounts for less than 3% of all cancers. despite recent improvement in diagnostic and treatment methods, the overall survival of the disease is unfavorable. several studies have been performed to assess factors influencing lymph node metastasis and prognosis. the aim of this study was to evaluate some clinical and pathological factors influencing lymph nod...

the gastrointestinal stromal tumor (gist) is a rare mesenchymal tumor of gastrointestinal (gi) tract. this tumor has tendency to liver metastasis and peritoneal recurrence, however; the primarily lymph node involvement or metastasis is rare. here we reported a 17-years-old girl with multifocal gastric gist and multiple lymph node involvement at presentation and recurrence in celiac lymph nodes....

Summary: Adenosine through adenosine receptor have a crucial role in biology of lung cancer. Recent study indicated adenosine receptors have a crucial role in various aspect of lung cancer from cell growth and metastasis to modulation of apoptosis and it could be considered as a potential candidate for treatment of the lung cancer.