A study was designed to evaluate the frequency of complementary/alternative therapy (CAM) knowledge and usage in cancer patients. A 23-item survey questionnaire was administered to 494 patients who received chemotherapy in the medical oncology department of three hospitals between June 2011 and December 2011. After giving written informed consent, patients completed a selfadministered questionn...

Amid the tangible transformations within the knowledge era, seismic changes in the business model have taken place. These changes have led to the emergence of what is so called ‘knowledge business model’ (KBM). Utilisation of a new business model includes unique challenges and opportunities. Knowledge assets and information technology are embodied as the driving forces beyond application of KBM...

Calmodulin (CaM) is found to have the capability to bind multiple targets. Investigations on the association mechanism of CaM to its targets are crucial for understanding protein-protein binding and recognition. Here, we developed a structure-based model to explore the binding process between CaM and skMLCK binding peptide. We found the cooperation between nonnative electrostatic interaction an...

Photosynthetic characteristics and induction of crassulacean acid metabolism (CAM) by drought stress were investigated in Sedum album, Sedum stoloniferum and Rosularia elymaitica from Crassulaceae. Titratable acidity, malate content, phosphoenolpyruvate carboxylase (PEPC) activity and gas exchange parameters were determined in plants at the end and beginning of the photoperiod. Results showed t...

We have developed a Web-based interactive cam design package under the programming paradigm of the C language environment. This package was initially developed as a teaching and learning tool for educational use in an undergraduate Computer-Aided Mechanism Design course. Because the system is Web-based and implemented through a client/server model with the user interface through the Web browser...

Cell adhesion molecules (CAMs) may act as regulators of morphogenesis by constraining cell motion, forming borders, and controlling intercellular communications that lead to embryonic induction. This postulated causal role of CAMs in inductive events was tested here in an in vitro system of feather induction. In the developing chicken skin, an ectodermal sheet of epithelium interacts with mesod...

The liver cell adhesion molecule (L-CAM) and N-cadherin or adherens junction-specific CAM (A-CAM) are structurally related cell surface glycoproteins that mediate calcium-dependent adhesion in different tissues. We have isolated and characterized a full-length cDNA clone for chicken N-cadherin and used this clone to transfect S180 mouse sarcoma cells that do not normally express N-cadherin. The...

The majority of ovarian cancer patients present with advanced disease and despite aggressive treatment, prognosis remains poor. Significant improvement in ovarian cancer survival will require the development of more effective molecularly targeted therapeutics. Commonly, mouse models are used for the in vivo assessment of potential new therapeutic targets in ovarian cancer. However, animal model...