نتایج جستجو برای: cam assay

تعداد نتایج: 235695  

Journal: :Annals of Oncology 2023

COVID-19 pandemic has affected research activities, as a direct consequence of lockdown measures and the closure most university facilities. We have utilized CAM (Chick Chorio-Allantoic Membrane) assay over mouse models for our drug combination study. is minimally invasive to chicken embryo hence refinement model animal research. formed by fusion mesodermal layers two developmental structures: ...

2014
Fangfang Li Changjun Huang Zhenghe Li Xueping Zhou

In plants, RNA silencing plays a key role in antiviral defense. To counteract host defense, plant viruses encode viral suppressors of RNA silencing (VSRs) that target different effector molecules in the RNA silencing pathway. Evidence has shown that plants also encode endogenous suppressors of RNA silencing (ESRs) that function in proper regulation of RNA silencing. The possibility that these c...

2016
Devprabha Samrath Sanjay Shakya Nidhi Rawat Varsha Rani Gilhare Fateh Singh

AIM Objective of the present study was to isolate bovine herpes virus Type 1 (BHV-1) from semen of infected bull and to adapt it onto embryonated eggs and Madin-Darby bovine kidney (MDBK) cell line. Further, the virus was identified by agar gel immunodiffusion (AGID) test. MATERIALS AND METHODS Semen samples were collected from five BHV-1 positive bulls previously confirmed for the presence o...

Journal: :Micro & Nano Letters 2022

In this study, an attempt has been made to synthesize nanoemulsions using Trachyspermum ammi tincture. The nanoemulsion specifications are characterized by TEM, DLS, and zeta potential. anti-tumour cell toxicity effects of the biosynthesized evaluated chorioallantoic membrane (CAM) MTT assays, respectively. For CAM test, length number blood vessels around gelatine sponge. According DLS analysis...

2013
Hao Hong Christine Brown Stephen J Forman Michael Jensen

Ovarian cancer is responsible for the majority of gynecologic cancer deaths. Despite improvements in surgical approaches and the refinement of first-line cytotoxic combinations, the majority of patients diagnosed with advanced stage ovarian cancer eventually succumb to tumor recurrence. Thus, novel therapeutic approaches are desperately needed for this disease. With the growing recognition of t...

Journal: :Japanese journal of clinical oncology 2007
Yusuke Komi Osamu Ohno Yasuhiro Suzuki Mariko Shimamura Kentaro Shimokado Kazuo Umezawa Soichi Kojima

BACKGROUND Sangivamycin, an antibiotic with anti-tumor and anti-herpes virus activities by inhibiting both DNA/RNA synthesis and protein kinase C activity, was reported to suppress selectively DNA synthesis and growth of human umbilical vein endothelial cells and their tube formation in vitro. Here, to address the potential clinical use of sangivamycin in future, we investigated its anti-angiog...

2009
Ram K. Roy Prince P. Sharma

A series of Combretastatin A-4 analogues were synthesized in order to obtain new compounds with potential antiangiogenic activity. The structures of all synthesized compounds were confirmed by means of spectroscopical analytical techniques. All compounds were evaluated for their antiangiogenic activity by chorioallantoic membrane (CAM) assay method. The compounds showed significant antiangiogen...

Mohammadreza Bordbar, Narges Fakhimi, Roza Kamfiroozi, Sezaneh Haghpanah, Tahereh Zarei, Zahra Jaafari,

Abstract Background: Children suffering from cancer frequently use complementary and alternative medicine (CAM). Most of people do not disclose using CAM to their physicians as they fear to be blamed or prohibited using them. Some of these products may interfere with the conventional remedies. The aim of this study was to investigate the frequency and characteristics of CAM ...

Journal: :Toxicological sciences : an official journal of the Society of Toxicology 2003
John M Rogers Barbara D Abbott

Cigarette smoking is unrivaled among developmental toxicants in terms of total adverse impact on the human population. According to the American Lung Association, smoking during pregnancy is estimated to account for 20–30% of low-weight babies, up to 14% of preterm deliveries, and about 10% of all infant deaths (http://www.lungusa.org/tobacco/pregnancy_ factsheet99.html). Both active (Stillman ...

2012
JING - TAO ZHANG YUE - ZU FAN CHUN - QIU CHEN ZHE - MING ZHAO WEI SUN

Our objective was to explore the antiangiogenic activity of norcantharidin (NCTD) as an angiogenic inhibitor for gallbladder cancers. In vitro and in vivo experiments to determine the effects of NCTD on HUVECs, chicken CAM capillaries and gallbladder cancer xenograft angiogenesis in nude mice were respectively done. The MTT method was used to assay the cytotoxicity of NCTD on HUVECs. Immunofluo...

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