An increased susceptibility to disease is one hypothesis explaining how inbreeding hastens extinction in island endemics and threatened species. Experimental studies show that disease resistance declines as inbreeding increases, but data from in situ wildlife systems are scarce. Genetic diversity increases with island size across the entire range of an extremely inbred Galápagos endemic bird, p...

studbook information collected from 1988 to 2011 in jafarabad breeding station of moghani sheep, north-west of iran, related to 9,457 lambs were used to study the genetic diversity and to evaluate the effectiveness of an implemented rotational mating scheme using pedigree analysis. lambs born during 2009-2011 were considered as reference population. means inbreeding and average coancestry for t...

Inbreeding and relatedness in wild panda populations are important parameters for panda conservation. Habitat loss and fragmentation are expected to increase inbreeding but the actual inbreeding levels in natural panda habitats were unknown. Using 150,025 SNPs and 14,926 SNPs selected from published whole-genome sequences, we estimated genomic inbreeding coefficients and relatedness of 49 panda...

The long-term study of animal populations facilitates detailed analysis of processes otherwise difficult to measure, and whose significance may appear only when a large sample size from many years is available for analysis. For example, inbreeding is a rare event in most natural populations, and therefore many years of data are needed to estimate its effect on fitness. A key behaviour hypothesi...

Although numerous studies on vertebrates suggest that inbreeding reduces their resistance against parasites and pathogens, studies in insects have found contradictory evidence. In this study we tested the effect of 1 generation of brother-sister mating (inbreeding) on potential and realized immune responses and other life-history traits in Tenebrio molitor. We found that inbreeding reduced adul...

Purdue University Cooperative Extension Service West Lafayette, IN 47907 Author: David S. Buchanan, Oklahoma State University, Reviewers: Kreg Leymaster, USDA MARC, Clay Center NE; Ken Stalder, Univ. of Tennessee, Jackson, TN; William Luce, Oklahoma State Univ., Stillwater, OK Inbreeding is the mating of individuals that are related. In the strict sense, all members of a breed are related. As a...

Congenital heart disorders (CHDs) are an important health issue due to heavy costs and emotional effects they impose to families and society. In general, the prevalence of CHDs is approximately 8 in 1000 newborn, with a multifactorial origin. On the other hand, previous studies have shown that the prevalence of CHDs is high among the children of parents with consanguineous marriage. The aim of ...

Inbreeding depression refers to the reduction of fitness that results from matings between relatives. Evidence for reduced fitness in inbred individuals is widespread, but the strength of inbreeding depression varies widely both within and among taxa. Environmental conditions can mediate this variation in the strength of inbreeding depression, with environmental stress exacerbating the negative...