Resumen El linfoma de Burkitt es un no Hodgkin células B, que representa el 4% la patología tumoral. Existen tres formas clínicas, siendo esporádica más frecuente en nuestro medio, sobre todo niños o adultos jóvenes. Describimos caso pancreático y ovárico, clínica debut ictericia asintomática lo determina inicio del estudio. Como resultados conclusión, destacar una entidad poco i...

The transcription factor KLF4 may act both as an oncogene and a tumor suppressor in a tissue-depending manner. In T- and pre-B-cell lymphoma, KLF4 was found to act as tumor suppressor. We found the KLF4 promoter methylated in B-cell lymphoma cell lines and in primary cases of B-cell lymphomas, namely, follicular lymphoma, diffuse large B-cell lymphoma, Burkitt lymphoma, and in classic Hodgkin l...

Histologic transformation (HT) refers to a biologic event leading to the development of a high-grade, aggressive non-Hodgkin lymphoma in patientswith anunderlying follicular lymphoma (FL). Transformation to diffuse large B-cell lymphoma (DLBCL) or Burkitt lymphoma is also known to take place in other subtypes of indolent lymphoma such as marginal zone lymphoma, lymphoplasmacytic lymphoma, small...

Using an improved electroimmunofixation technique that combines the sensitivity of high resolution agarose gel electrophoresis with the specificity of immunoprecipitation, we have demonstrated monoclonal immunoglobulin bands in the serum of patients with undifferentiated lymphomas of Burkitt and non-Burkitt types. Monoclonal bands were detected in the serum of 12 of 21 patients with extensive t...

Burkitt lymphoma is a fast-growing Non-Hodgkin's Lymphoma that originates from mature B cells. It is generally associated with chromosomal translocations or/and Epstein– Barr virus infection leading to deregulated activation of the c-myc oncogene. Combination chemotherapy with a vincristine-containing regimen is the treatment of choice in Burkitt lymphoma, however, only 50% of the patients resp...

Diffuse peritoneal and especially periportal invasion of Burkitt lymphoma is very rarely seen. We present a case 16-year-old boy presenting with abdominal pain constipation, without improvement after enemas. Abdominal ultrasound revealed diffuse infiltrating mass, omental caking, ascites, confirmed by computed tomography (CT). No lymphadenopathies were Biopsy was performed the diagnosis made. A...