Understanding local pulmonary immunoregulatory mechanism(s) in patients with carcinoma of the lung is an important step towards the development of innovative methods of treatment. Prostaglandin E2 plays an integral role in immunoregulation. Therefore, we evaluated PGE2 concentrations in BALF from 18 patients with bronchogenic carcinoma, compared to that from six patients with pulmonary diseases...

OBJECTIVE To investigate the association between bird keeping and risk of lung cancer. DESIGN Case-control study asking detailed questions on exposure to domestic birds and other pets, smoking, and various demographic and potentially confounding variables. SETTING District general hospital; current admissions interviewed in hospital or recent admissions interviewed at home. PATIENTS 143 p...

C ytologic examination of sputum has long been used in the diagnosis of bronchogenic carcinoma. Tumors of the segmental and larger bronchi may shed cells detectable in the sputum for many months prior to becoming symptomatic or radiographically apparent.’ During this period of their development, standard endoscopic techniques have frequently proven inadequate to localize the lesion with suffici...