A cross sectional study was conducted among 1007 children aged 1-2 years, from padi farming area. The percentage of male children was 51.4%. The prevalence of at least one of the chronic respiratory symptoms was 12.81%, and the prevalence of chronic cough, chronic sputum, wheezing and bronchial asthma as diagnosed by doctors were 9.33%, 3.87% 5.36% and 3.38% respectively. The overall prevalence...

Background: Asthma is an allergic airway inflammatory disease in which B cell activation plays a pivotal role. CXCL13 is a family member of CXC chemokines involved in B cell differentiation and activation. The purpose of this research is to explore the correlation between serum CXCL13 levels and the severity of the disease. Methods: A total of 31 patients with acute bronchial asthma, 29 patient...

BACKGROUND Cysteinyl-leukotrienes are mediators of inflammatory responses in bronchial asthma. We studied the genes encoding the enzymes involved in their synthesis to identify risk factors for asthma. The promoter polymorphisms LTC4S -444 A/C, ALOX5 -176/-147, and ALOX5AP -169/-146 have been reported to be associated with bronchial asthma. METHODS We analyzed the effects of LTC4S -444 A/C, A...

451 TheRelationship BetweenEmotional Cognition and the Symptom Gap inPatientswithBronchialAsthma: theEffects ofAlexithymia and Empathy Sonomi Nakajima. Clinical Psychology, Graduate School of Human Sciences, Osaka University, Suitashi, Japan. Background: When symptoms are poorly controlled, patients with bronchial asthma may show a symptom gap: a cognitive divergence between the true severity o...

451 TheRelationship BetweenEmotional Cognition and the Symptom Gap inPatientswithBronchialAsthma: theEffects ofAlexithymia and Empathy Sonomi Nakajima. Clinical Psychology, Graduate School of Human Sciences, Osaka University, Suitashi, Japan. Background: When symptoms are poorly controlled, patients with bronchial asthma may show a symptom gap: a cognitive divergence between the true severity o...

The pathogenetic mechanism of nonatopic asthma has not yet been defined. The idea of a possible involvement of autoimmunity in the pathogenesis of nonatopic asthma has been proposed by earlier studies. To evaluate the possible involvement of autoimmune response against bronchial epithelial cell in the pathogenesis of nonatopic asthma, we measured circulating autoantibodies to cultured human bro...

451 TheRelationship BetweenEmotional Cognition and the Symptom Gap inPatientswithBronchialAsthma: theEffects ofAlexithymia and Empathy Sonomi Nakajima. Clinical Psychology, Graduate School of Human Sciences, Osaka University, Suitashi, Japan. Background: When symptoms are poorly controlled, patients with bronchial asthma may show a symptom gap: a cognitive divergence between the true severity o...

BACKGROUND The significant value of tests used to certify the diagnosis of occupational asthma due to persulphate salts remains uncertain. AIMS To validate the specific inhalation challenge (SIC) test for the diagnosis of occupational asthma. METHODS Eight patients with occupational asthma due to persulphate salts, eight patients with bronchial asthma who were never exposed to persulphate s...

In the first half of the last century tuberculosis was the main focus of attention amongst all respiratory diseases. Bronchial asthma is a serious global health problem. The present study was carried out to estimate magnesium levels in serum in pulmonary tuberculosis and bronchial asthma cases and to compare them with the serum magnesium levels of controls. This study was undertaken in 120 subj...

AIMS To analyze the changes in the prevalence of asthma, bronchial hyperresponsiveness (BHR) and allergies in elite athletes over the past years, to review the specific pathogenetic features of these conditions and to make recommendations for their diagnosis. METHODS The Task Force reviewed present literature by searching Medline up to November 2006 for relevant papers by the search words: as...