background and objectives: the emergence of extended-spectrum β-lactamase (esbl)-producing shigella spp.  is of increasing clinical concern specially in children worldwide. the aim of this study was to investigate the occurrence of extended-spectrum β-lactamase producing shigella spp. in tehran, iran. materials and methods: the study included all shigella isolates recovered from pediatric patie...

The acquisition of beta-lactamases in members of the Enterobacteriaceae family poses a challenge to antimicrobial susceptibility testing in the clinical laboratory. We correlated the distribution of the MICs for Klebsiella spp. and Escherichia coli with the presence of extended-spectrum beta-lactamase (ESBL) and plasmid-mediated AmpC beta-lactamase (pAmpC) genes. A total of 264 isolates were su...

BACKGROUND AND OBJECTIVES Resistance to a wide variety of common antimicrobials has made the proliferation of Extended spectrum β-lactmase (ESBL) producing strains a serious global health concern that has complicated treatment strategies. The high proportion of ESBL producers among the Enterobacteriaceae and the complex molecular epidemiology with diverse types of ESBL genes are alarming. This ...

AIM To determine the prevalence and genotypic characterisation of extended spectrum beta-lactamases produced by gram negative bacilli isolated at Mbarara Regional Referral Hospital (MRRH). SAMPLES Gram negative clinical isolates. STUDY DESIGN Laboratory-based descriptive cross-sectional study. PLACE AND DURATION OF THE STUDY MRRH, June and August 2012. METHODS Gram negative clinical iso...

objective: the present study was conducted to detect possible chemicals (phytoconstituents), prove ethno-medicinal value of the plant, and investigate antimicrobial, anthelmintic, and total phenolic content of crude methanolic extract of the solanum violaceum plant.  materials and methods: phytochemical screening was carried out using different chemical group test methods. in anthelmintic activ...

BACKGROUND Studies about transmission rates of extended-spectrum β-lactamase (ESBL)-producing Enterobacteriaceae in hospitals and households are scarce. METHODS Eighty-two index patients with new carriage of ESBL-producing Escherichia coli (ESBL-Ec; n = 72) or ESBL-producing Klebsiella pneumoniae (ESBL-Kp; n = 10) and their hospital (n = 112) and household (n = 96) contacts were studied prosp...

KEYWORDS: Ceftolozane/tazobactamcomplicated urinary tract infectionsPseudomonas aeruginosaextended-spectrum beta-lactamases (ESBL)-producers

Ertapenem is active against extended-spectrum-β-lactamase (ESBL)-producing Enterobacteriaceae organisms but inactive against Pseudomonas aeruginosa and Acinetobacter baumannii. Due to a lack of therapeutic data for ertapenem in the treatment of ESBL bloodstream infections (BSIs), group 2 carbapenems (e.g., imipenem or meropenem) are often preferred for treatment of ESBL-producing Enterobacteria...

Purpose: To know the prevalence of extended spectrum βlactamases (ESBL) in multidrug resistant strains of Klebsiellapneumoniaefrom various clinical samples.Material and Methods: A total of 97 strains of Klebsiellapneumoniae were selected for the study, screened for ESBL and confirmed by phenotypic confirmatory disc diffusion test (PCDDT)Results: 92(94.84%) of isolates were resistant to one or m...

background extended-spectrum beta-lactamases (esbls) are a group of enzymes that hydrolyze antibiotics, including those containing new cephalosporins, and they are found in a significant percentage of escherichia coli and klebsiella pneumoniae strains. with the widespread use of antibiotics, difficulties with infection therapy caused by drug resistant organisms, especially those that have acqui...