OBJECTIVE The purpose of study was to prospectively evaluate the diagnostic performance of dynamic contrast-enhanced MR imaging in the differentiation of malignant lesions from benign ones in patients with BI-RADS 3-4 microcalcifications detected by mammography. MATERIALS AND METHODS 93 women with 100 microcalcifications had undergone breast MRI from June 2010 to July 2013. Subsequently, 91 r...

M e t h o d s Design: Blinded comparison of MRI and mammography for detecting breast cancer. Setting: 6 familial cancer clinics in the Netherlands. Patients: 1909 women who were 25 to 70 years of age (mean age 40 y) and had a cumulative lifetime risk for breast cancer ≥ 15% because of familial or genetic predisposition. Women < 25 years of age could be tested if they had a family history of bre...

The purpose of this study is to investigate whether an adjacent vessel sign (AVS) observed on the maximum intensity projections (MIPs) from the subtracted images can help distinguish between malignant and benign breast lesions and to test whether the combination of breast imaging reporting and data system (BI-RADS) category and AVS can increase the specificity and diagnostic accuracy of breast ...

OBJECTIVE The purpose of this study was to determine the MRI findings and histology of clinically and mammographically occult invasive breast cancers detected by MRI. MATERIALS AND METHODS A retrospective review was undertaken of 1,336 breast MRI examinations performed during a 2-year period. Among these, 68 nonpalpable mammographically occult invasive cancers were identified in 57 women with...

Dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) is increasingly being used for the detection and diagnosis of breast cancer. Compared to mammography, DCE-MRI provides higher sensitivity, however its specificity is variable. Moreover, DCE-MRI data analysis is time consuming and depends on reader expertise. The aim of this work is to propose a novel automated breast cancer localiza...

Breast metastases in cases of leukemia are rare. We aimed to report the conventional-advanced magnetic resonance imaging (MRI) findings of unilateral breast involvement of acute lymphoblastic leukemia (ALL) and review the literature. A 32-year-old woman was first diagnosed with ALL in treated in 2004. She did not continue the follow-up after 2008. She was presented with a giant, progressive rig...

Neoadjuvant chemotherapy (NACT) is a treatment used in those breast cancers initially inoperable due to their size, and also in operable breast cancers where NACT could increase the rate of conservative breast surgery. To assess tumor response to treatment, clinical examination, mammography, ultrasound, and breast MRI are used, the latter being the modality that yields the best correlation with...

After mammography and ultrasound (US), magnetic resonance imaging (MRI) of the breast is the third diagnostic imaging technique used in the diagnostic work-up of breast findings. In contrast to the other techniques, MRI primarily gives information on the vascularization of intramammary structures. Because malignant tumors typically have an increased vascularization attributed to tumor neoangiog...

One of the major roles of breast MRI in clinical practice has been in the evaluation of disease extent. The roles of mammography and sonography can be limited, especially in the presence of invasive lobular carcinoma and in the patient with positive margins postoperatively. Breast MRI has improved our detection of multicentric, multifocal, and concurrent contralateral disease. Dr. Gundry correc...