نتایج جستجو برای: brain derived neurotrophic factor

تعداد نتایج: 1678613  

2004
DEVIN K. BINDER HELEN E. SCHARFMAN

Nerve growth factor (NGF) was discovered in the early 1950s due to its trophic (survivaland growth-promoting) effects on sensory and sympathetic neurons (LeviMontalcini and Hamburger, 1951). In 1982, brain-derived neurotrophic factor (BDNF), the second member of the “neurotrophin” family of neurotrophic factors, was shown to promote survival of a subpopulation of dorsal root ganglion neurons, a...

2015
Kazuko Sakata

Increasing evidence over the last two decades has indicated that the pathophysiology of Major Depressive Disorder (MDD) and the action of antidepressants both involve Brain-Derived Neurotrophic Factor (BDNF), a major neuronal growth factor in the brain. MDD is a complex disorder that results from genetic and environmental influences, singly or in combination. This article reviews the current kn...

Fatemeh Alipour, Maryam Borhani-Haghighi, Parastoo Barati,

Post-traumatic stress disorder (PTSD) is a syndrome causing from a severe traumatic happening that leads to threatened death or injury. PTSD is associated with changes in limbic, hippocampal, and prefrontal cortical region function due to changes in synaptogenesis, dendritic modifying, and neurogenesis. Changes in neuron in PTSD patients result from pathophysiological disturbances in inflammato...

  Background: The balance between production of Reactive Oxygen Species (ROS) and antioxidant defense in the body has important health implications. The aim of this study was to investigate the changes in salivary antioxidants: catalase, vitamin C and brain-derived neurotrophic factor (BDNF), in sedentary men at rest and after acute exhaustive exercise.   Methods: This randomi...

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