Aim: Somatic symptom disorder (SSD) is a psychiatric with unknown etiopathogenesis that still under investigation. The results of neuroimaging studies on SSD have shown some brain regions may be associated it. In this connection, study aims to explore the orbitofrontal cortex (OFC) morphometric changes in patients better comprehend etiopathogenesis.
 Material and Methods: enrolled 20 healt...

Background: Brain imaging results in sleep deprived patients showed structural changes the cerebral cortex; however, reasons for this phenomenon need to be further explored. Methods: This MR study evaluated causal associations between morningness, ease of getting up, insomnia, long sleep, short and cortex structure. Results: At functional level, morningness increased surface area (SA) cuneus wi...

Purpose: To study the specific content (per 1 g of tissue) reduced glutathione and activity enzyme antioxidant protection peroxidase conjugated with it in various structural functional parts rat brain when exposed to ionizing radiation at a dose 6 Gy. Material methods: The studies were carried out on white outbred rats subjected single total γ-radiation an average lethal determined irradiated a...

Somatostatin receptor subtype 4 (SST4) has been shown to mediate analgesic, antidepressant and anti-inflammatory functions without endocrine actions; therefore, it is proposed be a novel target for drug development. To overcome the species differences of SST4 expression function between humans mice, we generated an humanized mouse line serve as translational animal model preclinical research. A...

A person, who is talented, performs in a certain capacity above the norm. Talent is different from intelligence which is a response to a circumstance using knowledge and skill. The attributes of talent are exceptional memory, rapid processing speed, and high motivation, an affinity for learning, creativity and optimal cognition. There is some proof suggests that certain aspects of talent are re...

DHIPC (2,4-dichloro-2´-hydroxyl-4´,6´-diisoprenyloxychalcone) is a new chalconecompound. In this study, its antidepressant-like activity of compound DHIPC was evaluated bythe forced swimming test and the tail suspension test in mice. The results showed that DHIPCsignificantly reduced the immobility time for 2 h after treatment through the oral administrationat dose of 10, 20, and 30 mg/kg in th...

Both the hippocampus and entorhinal cortex are involved in memory formation. It is thought that they work together to create a loop formation of long term memories. The sends projections CA1 field back cortex. How exactly communicate unknown. In order do electrophysiological studies it necessary know which orientation cut brain preserve most connections between these two areas. Here we show DiI...

According to various data, sports traumatic brain injury (TBI) accounts for up 20% of all injuries in athletes, and the number cases traumatization is progressively increasing year by due an increase people involved sports, growing popularity extreme contact as well a high level motivation achieve record results. The structure TBI dominated mild TBI, which can provoke development very wide rang...

The primary cilium, a microtubule based organelle protruding from the cell surface and acting as an antenna in multiple signaling pathways, takes center stage formation of cerebral cortex, part brain that performs highly complex neural tasks confers humans with their unique cognitive capabilities. These activities require dozens different types neurons are interconnected ways. Due to this compl...