BACKGROUND: The brain is very susceptible to damage from oxidative stress due undernutrition. Provision of nutrients and compounds that act as antioxidants needed improve in the brain. AIM: This study was conducted with aim proving potential combination pasak bumi (Eurycoma longifolia Jack), DHA, seluang fish (Rasbora Spp.) brains undernourished rats (Rattus norvegicus). METHODS: Once were unde...

  Background: The balance between production of Reactive Oxygen Species (ROS) and antioxidant defense in the body has important health implications. The aim of this study was to investigate the changes in salivary antioxidants: catalase, vitamin C and brain-derived neurotrophic factor (BDNF), in sedentary men at rest and after acute exhaustive exercise.   Methods: This randomi...

background: the balance between production of reactive oxygen species (ros) and antioxidant defense in the body has important health implications. the aim of this study was to investigate the changes in salivary antioxidants: catalase, vitamin c and brain-derived neurotrophic factor (bdnf), in sedentary men at rest and after acute exhaustive exercise.   methods: this randomized controlled clini...

Natural antioxidants compounds are present in leaf, rhizome, stem, fruits, vegetables, tea etc. They are recognized as important compounds in conferring stability against oxidation in vitro. Natural antioxidant compounds can be classified into Exogenous antioxidants and Endogenous antioxidants, Enzymatic and NonEnzymatic antioxidants. Naturally occurring antioxidants compounds are carotenoids, ...

The demand for high-quality seafood products is constantly growing worldwide. Nevertheless, seafood is susceptible to rapid rancidity mainly due to lipid oxidation and microbiological spoilage. Thus, treatment with antioxidants offers a preservation technique that can prolong the shelf life of seafood. However, because of food safety and health concerns about the use of synthetic antioxidants, ...

Lead is one of the metals whose toxicological effect in humans and animals is of clinical concerned as reported by researchers. Quite a number of chemical agents have been reported to ameliorate lead associated toxicological effects especially in animal studies. This literary study reviewed reported toxicological effect of lead on the liver, kidney and brain with emphasis on the roles of mitiga...

Effect of restraint stress (RS) and its modulation by antioxidants were evaluated on elevated plus maze (EPM) and open field (OF) tests in rats. Restraint stress (RS for 1 hr) reduced the number of open arm entries, as also the time spent on open arms indicating enhanced anxiogenic response in the EPM test as compared to normal non RS group of rats. Pretreatment with ascorbic acid (100 and 200 ...

In our search for novel, low-toxic, cell-penetrable and neuroprotective antioxidants, we have designed a number of novel N-propargylamine derivatives of nitroxyl, named "JSAKs". The reactivity and antioxidative potency of two selected JSAKs and their parent nitroxyl against reactive oxygen species (ROS) were examined in vitro, in a cell-free gamma-radiolysis and in model Fenton-type reaction sy...

Previous work has shown that a diet enriched with antioxidants and mitochondrial co-factors improves cognition in aged dogs, which is accompanied by a reduction in oxidative damage in the brain. The objective of the present study was to assess the effects of supplementation with mitochondrial co-factors on cognition and plasma protein carbonyl levels in aged dogs. Specifically, we aimed to test...