In 1993, noncytopathic bovine viral diarrhea virus (BVDV) strains with enhanced virulence caused unprecedented outbreaks of severe acute bovine viral diarrhea (BVD) in dairy, beef, and veal herds in Ontario (Canada). Fever, pneumonia, diarrhea, and sudden death occurred in all age groups of cattle. Abortions often occurred in pregnant animals. Gross lesions in the alimentary tract were similar ...

We report DNA immunisation experiments in cattle using plasmid constructs that encoded glycoprotein E2 from bovine viral diarrhoea virus (BVDV)-1 (E2.1) and BVDV-2 (E2.2). The coding sequences were optimised for efficient expression in mammalian cells. A modified leader peptide sequence from protein gD of BoHV1 was inserted upstream of the E2 coding sequences for efficient membrane export of th...

in order to study the seroprevalence of pestivirus infection in small ruminants of ahvaz at khouzestan province of iran, 148 sheep sera and 143 goat sera were randomly collected and tested by seroneutralization. seroneutralization was performed by nadl strain of bovine viral diarrhea virus genotype 1. the results indicated the overall seroprevanelces of 46.62% in sheep and 32.871% in goats. pre...