BACKGROUND Sulfur mustard can cause several long-term complications in the organs of individuals exposed to this toxic gas, and among these, pulmonary sequelae are the most important. More than 25 years after the Iran-Iraq war, thousands of Iranians are suffering from the chronic respiratory complications of sulfur mustard. Currently, based on several clinical findings, bronchiolitis obliterans...

UNLABELLED BACKGROUND The 11S globulin Sin a 2 is a marker to predict severity of symptoms in mustard allergic patients. The potential implication of Sin a 2 in cross-reactivity with tree nuts and peanut has not been investigated so far. In this work, we studied at the IgG and IgE level the involvement of the 11S globulin Sin a 2 in cross-reactivity among mustard, tree nuts and peanut. MET...

Sulfur mustard, a potent inhibitor of two-stage skin tumorigenesis, appears to act primarily by inactivating initiated cells rather than by suppressing the biochemical response to the promoter ^-O-tetradecanoylphorboMSacetate (TPA). Thus, when the increase of epidermal-dermal p-tosyl-L-arginine methyl ester esterase activity in TPAtreated mice was compared with the response of mice similarly tr...

We recently published electron paramagnetic resonance (EPR) spin trapping results that demonstrated the enzymatic reduction of sulfur mustard sulfonium ions to carbon-based free radicals using an in vitro system containing sulfur mustard, cytochrome P450 reductase, NADPH, and the spin trap α-(4-pyridyl-1-oxide)-N-tert-butylnitrone (4-POBN) in buffer (A.A. Brimfield et al., 2009, Toxicol. Appl. ...

An open, continuous flow system was used to investigate ethylene production during degreening of maturing seed of mustard (Brassica juncea cv Cutlass and cv Lethbridge 22A) and canola (Brassica napus cv Westar and cv Alto). Isolated mustard seed evolved higher amounts of ethylene than those of canola, and this was particularly evident both early in embryogeny and later during the desiccation ph...

This study offers comprehensive details on the use of bio-fuel as a viable and alternative source of energy. The bio-fuel was prepared from vegetable oil, i.e., mustard oil and tested in a diesel engine in both pure form and as a diesel blend. The mustard oil blend proportions were 20%, 30%, 40% and 50% and named as bio-diesel blends B20, B30, B40 and B50. A fuel-testing laboratory determined t...

A tumoricidal system has been described utilizing a two-step process which, first, specifically alters the antigenic nature of a tumor cell and, second, adds a heterologous cytotoxic anti body without affecting normal cells. The antigenic structure of the tumor cell is altered by the nitrogen mustard, L-phenylalanine mustard, and a specific antibody is made to this mustard by injecting it into ...

The effects of treatment with various doses of carcinostatic agents on tumor growth have been studied. In animal experiments. treatment with low concentrations of nitrogen mustard N-oxide resulted in an early death of mh:e bearing Ehrlich ascites carcinoma and an increase in the number of circulating Yoshida sarcoma cells. The growth of subcutaneously implanted Yoshida sarcoma was stimulated af...

We studied the effect of prior corneal herpes simplex infection with its resultant corneal hypesthesia on the irritative response of the rabbit eye to topical nitrogen mustard. Both the miosis and the breakdown of the blood-aqueous barrier that follow the application of topical nitrogen mustard were diminished in eyes infected three weeks previously with herpes simplex virus. Nonspecific cornea...

Sulphur mustard is a chemical warfare agent, which was largely used during the World War One and in Iraq-Iran conflict. It may also be used as a chemical terrorism agent. Therefore, medical professions should have sufficient knowledge and be prepared for medical intervention of any such chemical attack.Sulphur mustard exerts direct toxic effects on the eyes, skin, and respiratory tract, with su...