Beneficial Management Practices (BMPs) are important measures for reducing agricultural non-point source (NPS) pollution. However, selection of BMPs for placement in a watershed requires optimizing available resources to maximize possible water quality benefits. Due to its iterative nature, the optimization typically takes a long time to achieve the BMP trade-off results which is not desirable ...

a series of copper and cobalt substituted nanospinel ferrites have been synthesized by the hydrothermal method. these compounds were characterized by ft-ir, xrd, edx, sem and vsm techniques. all of the synthesized nanospinel ferrites were found to be highly efficient and magnetically recoverable in the solvent-free synthesis of substituted 2,6-(2-hydroxybenzyl)-phenols (trisphenols). a wide ran...

Bone morphogenetic proteins (BMPs) have diverse and important roles in the proliferation and differentiation of adult stem cells in our tissues. Especially, BMPs are well known to be the main inducers of bone formation, by facilitating both proliferation and differentiation of bone stem cells. Interestingly, in skin stem cells, BMPs repress their proliferation but are indispensable for the prop...

Dorsal axial formation during vertebrate embryogenesis exhibits robust resistance to perturbations in patterning signals. However, how such stability is supported at the molecular level remains largely elusive. Here we show that Xenopus ONT1, an Olfactomedin-class secreted protein, stabilizes axial formation by restricting Chordin activity on the dorsal side. When ONT1 function is attenuated, t...

Magnetic nanoparticles are widely used in bioapplications such as imaging and targeting tool. Their magnetic nature allows for the more efficient bioapplications by an external field gradient. However their combined effects have not yet been extensively characterized. Herein, we first demonstrate the biological effects of the communications between internalized bacterial magnetic nanoparticles ...

Bone morphogenetic proteins (BMPs) are soluble effectors of differentiation and are central in orchestrating development of organs including the cerebellum. The transcription factor and BMP target Math1 (mouse atonal homolog 1) is a critical regulator of neuronal progenitors destined to form the cerebellar cortex. Signaling networks controlled by BMPs, Math1, and Sonic Hedgehog (Shh) together r...

We evaluate the impacts of different nutrient management strategies on potential for co-managing estrogens and nutrients in environmental waters Potomac watershed Chesapeake Bay. These co-management approaches represent agricultural urban runoff, wastewater treatment plant effluent, combined sewer overflow replacements. Twelve estrogenic compounds their metabolites were analysed by gas chromato...

BACKGROUND Initially identified for their capability to induce heterotopic bone formation, bone morphogenetic proteins (BMPs) are multifunctional growth factors that belong to the transforming growth factor β superfamily. Using cellular and molecular genetic approaches, recent studies have implicated intra-ovarian BMPs as potent regulators of ovarian follicular function. The bi-directional comm...

BACKGROUND Tendon disease is characterized by the development of fibrosis. Transforming growth factor beta (TGF-β), bone morphogenic proteins (BMPs) and connective tissue growth factor (CTGF) are key mediators in the pathogenesis of fibrotic disorders. The aim of this systematic review was to investigate the evidence for the expression of TGF-β, BMPs and CTGF along tendon disease progression an...