The recent financial crisis has raised questions regarding the role credit rating agencies play in monitoring the quality of corporate debt. Utility industry deregulation serves as a natural testing ground for evaluating the prudence of rating agencies and their monitoring process. Following deregulation and the Enron scandal, the general opinion among industry professionals is that utilities a...

Understanding BMG formation equates to being able explain their initiation as well subsequent evolution. Several scenarios of bedrock mega-groove (BMG) are proposed here, which attempt how such parallel fluted terrain could be incised through resistant substrates over the relatively short temporal periods associated with uni-directional fast ice flow. In cases where geological controls have bee...

COMMENT The May-June 2016 issue of the International Braz J Urol presents original contributions with a lot of interesting papers in different and as usual the editoŕs comment highlights some papers. We decided to comment 2 papers about a very usual topic in urologic practice: The Urethral Stricture. Doctor Prabha and collegues from India performed on page 564 an interesting study about the sin...

The AT specific minor grove DNA binding ligands bisbenzimidazole derivatives like hoechst-33342 and hoechst-33258 which scavenge free radicals and stabilize macromolecular structure have been shown to afford radioprotection by reducing the induction of DNA damage. However, their ability to inhibit topoisomerases I & II, which play important roles in damage response pathways including DNA repair...

BACKGROUND Plaque incision and tunical grafting is widely used to correct penile curvatures secondary to Peyronie's disease (PD), but there is no consensus on the ideal graft to be used. OBJECTIVE To evaluate the efficacy, safety, and reproducibility of plaque incision and buccal mucosa grafting (BMG) in the correction of severe penile curvatures secondary to PD. DESIGN, SETTING, AND PARTIC...

DNA ligand Hoechst-33342 significantly enhances UV induced cytotoxicity in human glioma cell lines (BMG-1 & U-87) with supra additive increase in cell death, cytogenetic damage, cell cycle delay, apoptosis and inhibition of PLDR. Cytotoxicity of Hoechst-33342 arises due to its interference in the breakage-rejoining reaction of DNA topoisomerases by stabilization of cleavable complexes. Since to...

A great expansion in the number of alloy compositions known to give bulk metallic glasses (BMGs) has occurred in recent years. This progress is reviewed, and factors contributing to glass-forming ability are discussed. Practical strategies for pinpointing compositions with optimum glass-forming ability are presented, with examples of their use. Consideration is also given to the wide range of p...

will preside Professor P. Balaram, Director Date : Tuesday, 11th October 2011 Venue : Faculty Hall, Main Building Time : 4-00 p.m INDIAN INSTITUTE OF SCIENCE BANGALORE Fracture Behaviour of Bulk Metallic Glasses Cordially invites you to the on by Professor Narasimhan Ramarathnam Department of Mechanical Engineering INSTITUTE COLLOQUIUM Tea: 5-15 p.m Reception Hall Bulk Metallic Glasses (BMGs) a...

AIM Review of our experience and to develop an algorithm for salvage procedures in the management of hypospadias cripples and treatment of urethral strictures following hypospadias repair. METHODS This is a retrospective review of hypospadias surgeries over a 41-month period. Out of a total 168 surgeries, 20 were salvage/re-operative repairs. In three children a Duplay repair was feasible, wh...