An 81-year-old Japanese man presented with dark blue papules and nodules on his face. There were multiple soft papules and nodules, dark blue in color, compressive, and ranging in size from 2 to 10 mm. A few similar lesions were seen on the patient's right dorsal second toe and right buccal mucosa. There were no skin lesions on his trunk and upper limbs. The patient's past history did not inclu...

The aim of our study is to enhance the awareness of blue rubber bleb nevus syndrome (BRBNS) through the patients in our hospital and introduced a new measure of endoscopic intervention.A retrospective review of 5 patients, who were diagnosed as BRBNS in our hospital from January 2013 to January 2017, was conducted. Data were collected with regard to demographics, clinical presentation, endoscop...

a Médico Adscrito Cirugía Endoscópica. Hospital General Dr. Manuel Gea González, S.S.A. México, D.F b Jefe de la División de Atención médica. Hospital General Dr. Manuel Gea González, S.S.A. México, D.F c Jefe del Servicio de Endoscopia Digestiva. Hospital General Dr. Manuel Gea González, S.S.A. México, D.F d Residente Motilidad Gastrointestinal. Hospital General Dr. Manuel Gea González, S.S.A....

Blue rubber bleb nevus syndrome (BRBNS) is a rare disorder characterized by distinctive cutaneous and gastrointestinal venous malformations that usually cause massive or occult gastrointestinal hemorrhage and iron deficiency anemia secondary to the bleeding episodes. Only two reports of BRBNS in pregnant women can be found, according to the MEDLINE search. Both cases did not describe severe com...

A 24-year-old woman presented having had soft, blue nodules on the palm of her hand (▶Fig. 1), lower limbs, and feet since birth. The number and size of the lesions had increased a little as she had grown up. She had suffered repeated episodes of intermittent melena or tarry stools since the age of 10 years, which had been accompanied by symptoms of pallor, dizziness, fatigue, and anorexia. In ...

To the Editor, Blue rubber bleb nevus syndrome (BRBNS) is a rare disorder characterized by distinctive cutaneous and gastrointestinal cavernous hemangiomas. Patients usually present with iron deficiency anemia from occult gastrointestinal bleeding or massive gastrointestinal bleeding in the emergent setting. Optimal management for these patients is unclear as a result of its rarity and anecdota...

BACKGROUND Blue rubber bleb nevus syndrome (BRBNS) is characterized by distinctive vascular malformations of skin and the gastrointestinal tract, often leading to chronic anemia and intestinal bleeding. It usually presents right after birth or during early infancy. Though the disease is inherent, its occurrence is sporadic. Thus it is usually not timely diagnosed. We analyzed the clinical chara...