journal of law, medicine & ethics Background Most babies born each year in the U.S. undergo mandatory newborn screening to detect serious medical conditions that can cause devastating effects if treatment is not initiated prior to the onset of symptoms.1 Not all of the blood collected from newborns is used during routine newborn screening, and many states retain the residual dried blood samples...

Simultaneous blood samples from an artery, a peripheral vein and a central vein were analysed for ICI 35868 concentrations following an induction dose of 2.0 mg kg-1 administered i.v. over 60 s, to five patients before cardiac surgery. Up to 60 s after the end of the administration of the drug there were wide differences in drug concentration between the sampling sites. Thus, any attempt to cor...

BACKGROUND Choline is critical for a variety of biological functions and has been investigated as a biomarker for various pathological conditions including acute coronary syndrome. METHODS A liquid chromatography-tandem mass spectrometry (LC-MS/MS) method was used to quantify choline in whole blood and plasma in freshly collected samples prepared with ultrafiltration or protein precipitation....

The only significant advances in blood-taking in 25 years have been the disposable needle and evacuated blood-drawing tube. With the exception of a few isolated barcode experiments, most sample-tracking is performed through handwritten or computer-printed labels. Attempts to reduce the hazards of centrifugation have resulted in air-tight lids or chambers, the use of which is time-consuming and ...