Properties of copolymers are generally influenced by the structure of the monomers and polymers. For the purpose of understanding the effect of polymer structure on the properties, two kinds of copolymers, poly(3,4-dihydroxyphenylalanine)-g-polylactide and poly(3,4-dihydroxyphenylalanine)-b-polylactide (PDOPA-g-PLA and PDOPA-b-PLA) were designed and prepared by ring-opening polymerization of la...

In this era of portability and rapid technological advances, polymers are more than ever under pressure to be cheap and offer tailored property profiles. Often, the key lies in designing blends and alloys carefully structured at the appropriate scale (preferably less than a micrometre) from existing polymers. Block copolymers - two or more different polymer chains linked together - have long be...

Self-assembly of block copolymers is a powerful motif for spontaneously forming well-defined nanostructures over macroscopic areas. Yet, the inherent energy minimization criteria of self-assembly give rise to a limited library of structures; diblock copolymers naturally form spheres on a cubic lattice, hexagonally packed cylinders and alternating lamellae. Here, we demonstrate multicomponent na...

Abstract Block copolymers are well recognized as excellent nanotools for delivering hydrophobic drugs. The formulation of such delivery nanoparticles requires robust characterization and clarification the critical quality attributes correlating with safety efficacy drug before applying to regulatory authorities approval. Static solution scattering from block is one technique. This paper first o...

Many studies have focused on how drugs are formulated in the sol state at room temperature leading to the formation of in situ gel at eye temperature to provide a controlled drug release. Stimuli-responsive block copolymer hydrogels possess several advantages including uncomplicated drug formulation and ease of application, no organic solvent, protective environment for drugs, site-specificity,...

The phase behavior of binary blends composed A 1 B and 2 diblock copolymers is systematically studied using the polymeric self-consistent field theory, focusing on formation relative stability various spherical packing phases. results are summarized in a set diagrams covering large space system. Besides commonly observed body-centered-cubic phase, complex phases including Frank–Kasper A15, ? La...

Chirality-driven microphase-separated morphology, poly(l-lactide) (PLLA) left-handed nanohelices hexagonally packed in PS matrix, was obtained from chiral diblock copolymers, poly(styrene)-b-poly(l-lactide). This is perhaps for the first time; the helical superstructures of chiral block copolymers were generated in the bulk and self-assembled to a two-dimensionally (2D) packed lattice. Now, the...

For the last decades, amphiphilic block copolymers have been at the focus of extensive scientific interest, due to their unique properties and numerous potential applications. Their technological potential evolves from their ability to self-assemble into a plethora of morphologically diverse nanostructures such as micelles, polymersomes, cylinders and others. In this chapter, we discuss the bas...