BACKGROUND The purpose of this study was to assess the possible role of major stressful life events, complicated grief, and depression in the pathogenesis of benign essential blepharospasm (BEB) and hemifacial spasm (HFS). METHODS This was a case-control study involving 23 participants with BEB/HFS and 23 control subjects, comparing the frequency of major stressful life events, depression on ...

Methods: Lacosamide (Vimpat), a recently released, novel anticonvulsant was used to treat one patient with hemifacial spasm and a second patient with both benign essential blepharospasm and hemifacial spasm. Lacosamide selectively enhances the slow inactivation of voltage-gated sodium channels resulting in stabilization of hyperexcitable neuronal membranes and inhibition of repetitive neuronal ...

 The major route of exposure is by inhalation.  Acute inhalation exposure to bromine vapour may cause upper respiratory effects, cough, headache, CNS effects and lacrimation.  Acute oral exposure to bromine results in central nervous system effects.  Deep partial skin loss and skin discolouration have been reported following acute dermal exposure to bromine.  Ocular exposure to bromine cau...

Meige's syndrome consists of idiopathic blepharospasm and oromandibular dystonia. The exact etiology is not known and various hypotheses have been proposed for its causation. The hypothesis suggesting dopaminergic and cholinergic hyperactivity is most widely accepted. There is no curative drug for Meige's syndrome although a variety of treatments have been proposed. We report a case which respo...