A common topic in clinical anticoagulation research used to be bleeding risk in old age. Times have changed, as well as the population of patients on anticoagulants, and the topic now is bleeding risk in very old patients. What is it about age that stimulates clinical investigators to launch studies of age and bleeding risk with vitamin K antagonist (VKA) therapy? First, the decision to initiat...

BACKGROUND The aim of this study was to evaluate the efficacy and safety of herbal dental cream in comparison to fluoride dental cream. OBJECTIVES Clinical evaluation of a novel herbal dental cream in plaque formation: a double-blind, randomized, controlled clinical trial. METHODS One hundred and two patients with established dental plaque were randomly assigned to either herbal dental grou...

OBJECTIVES The authors sought to describe the association between post-procedural bleeding and long-term recurrent bleeding, major adverse cardiac events (MACE), and mortality among older patients undergoing percutaneous coronary intervention (PCI). BACKGROUND Bleeding complications after PCI are associated with an increased risk for acute morbidity and long-term mortality, but the associatio...

Objective: Abnormal uterine bleeding (AUB) is a common problem among women in reproductive age. Not always is their cause easy to establish and in those cases not yet classified abnormal uterine bleeding is diagnosed. The aim of this study was the analysis of the clinical and histopathological results of the endometrium evaluation in women with initially diagnose of not yet classified bleeding ...

BackgroundFor patients with atrial fibrillation (AF) having ischemic stroke or transient attack (TIA) despite taking direct oral anticoagulants (DOAC), the optimal strategy for ongoing anticoagulation is unknown.MethodsUsing provincial administrative databases in Alberta, Canada, we compared anticoagulant use before/after breakthrough stroke/TIA and assessed recurrence of bleeding, consideratio...

Gastroesophageal varices are present in 50% of patients with cirrhosis, and variceal hemorrhage develops in up to one third of these patients. The risk of variceal hemorrhage is increased in patients who have large varices and advanced stages of liver disease, as assessed on the basis of the Child– Pugh class.1 Several studies published between 1942 and 1981 showed poor outcomes after variceal ...

Abstract We conducted a retrospective analysis of 497 patients who underwent tonsillectomy at Kamio Memorial Hospital from September 2015 to August 2018. A total 35 cases (7.0%) developed postoperative bleeding and three (0.6%) needed second operation under general anesthesia stop the bleeding. Postoperative most frequently occurred between 24 hours 6 days after operation. The incidence was sig...

Leukemia has been associated with oral manifestations. However, the available literature on this topic consists of mostly reports of cases, without data about the periodontal parameters that may be under the influence of hematologic factors. The aim of this cross-sectional study was to assess the correlation between the Gingival Index and Bleeding on Probing with the platelet count in patients ...

The use of topical NSAIDs to complement periodontal therapy could help resolve the inflammatory process and clinical signs of the disease more rapidly. A randomized clinical trial was performed on 59 patients, of whom 33 had chronic periodontitis and 26 were healthy controls. All diseased patients underwent scaling and root planing in one quadrant per week with subgingival application of gel 48...

STATEMENT OF PROBLEM Fixed orthodontic appliances in the oral cavity make tooth cleaning procedures more complicated. OBJECTIVES This study aimed to compare the efficacy of computerized oral hygiene instruction with verbal technique among fixed orthodontic patients referred to the evening clinic of Orthodontics of Shiraz Dental School. MATERIALS AND METHODS A single-blind study was performe...