We report on posttransplant relapsed pediatric patients with B-precursor acute lymphoblastic leukemia with no further standard of care therapy who were treated with the T-cell engaging CD19/CD3-bispecific single-chain antibody construct blinatumomab on a compassionate use basis. Blast load was assessed prior to, during and after blinatumomab cycle using flow cytometry to detect minimal residual...

considerations on the explosion resistant design of special infrastructures have increased in the recent years. amongst the various types of infrastructures, road and railway tunnels have a unique importance due to their vital role in connection routes in emergency conditions. in this study, the explosion effects of a projectile impacting on a railway tunnel located in a jointed rock medium has...

Explosions increasingly occur in densely populated, urban locations. Primary blast injuries (PBIs), caused by exposure to wave overpressure, can be predicted using injury criteria, although many are based on idealised loading scenarios that do not necessarily reflect real life situations. At present, there is limited understanding of how, and what extent, blast-structure interaction influences ...

blast (magnaporthe grisea) is the most important disease of rice in mazandaran province, north of iran, which causes severe damages annually on susceptible cultivars. tarom mahalli is a local aromatic cultivar with high cooking quality and marketability, but very susceptible to blast. to protect this cultivar and similar susceptible cultivars against rice blast, farmers have to use high amounts...

grain yield loss in rice (oryza sativa l.) caused by blast disease, magnaporthe grisea (hebert) barr, is a major concern of rice growers worldwide. blast is considered as the most injurious disease of rice in iran, resulting in severe loss especially to susceptible rice cultivars. in order to assess yield loss caused by blast pathogen and develop an appropriate model, different disease onsets a...

Abstract Blended concretes, with the partial replacement of cement secondary cementitious material like fly ash, rice husk GGBS (Ground Granulated Blast Slag), silica fume etc. are gaining a wide range applications in civil engineering nowadays. The behaviour concrete structures has been studied by many researchers under different types loads impact load, wind earthquake load Impact loading ana...

Abstract The aircraft gun firing will cause serious impact on airframe structure. According to the principle, muzzle blast wave is simulated by chemical explosion. ALE method used deal with fluid-structure interaction between high-pressure flowing air and surface of cabin. Then expression model load established. numerical calculation completed analyse dynamic response cabin structure under load...

To assist the bioinformatic community in leveraging the national cyberinfrastructure, the National Center for Genomic Analysis Support (NCGAS) along with Indiana University's High Throughput Computing (HTC) group have engineered a method to use the Galaxy to submit BLAST jobs to the Open Science Grid (OSG). OSG is a collaboration of resource providers that utilize opportunistic cycles at more t...

DEVELOPMENT OF LOWER EXTREMITY INJURY CRITERIA ANDBIOMECHANICAL SURROGATE TO EVALUATE MILITARY VEHICLE OCCUPANTINJURY DURING AN EXPLOSIVE BLAST EVENTbyBRIAN JOSEPH MCKAYDecember 2010Advisor: Dr. Cynthia BirMajor: Biomedical EngineeringDegree: Doctor of Philosophy Anti-vehicular (AV) landmines and improvised explosive devices (IED) haveaccounted for more than ...