PURPOSE Clavicular shortening after fracture is deemed prognostic for clinical outcome and is therefore generally assessed on radiographs. It is used for clinical decision making regarding operative or non-operative treatment in the first 2weeks after trauma, although the reliability and accuracy of the measurements are unclear. This study aimed to assess the reliability of roentgen photogramme...

BACKGROUND Monitoring urine protein:creatinine ratios (UPC) in dogs with protein-losing nephropathy (PLN) is challenging because of day-to-day variation in UPC results. HYPOTHESIS/OBJECTIVES Determine whether single, averaged, or pooled samples from PLN dogs receiving medical treatment yield comparable UPCs, regardless of degree of proteinuria. ANIMALS Twenty-five client-owned PLN dogs rece...

objective: measurement of glomerular filtration rate (gfr) is the best determinant in assessment of kidney function for diagnostic and therapeutic purposes. as extremely accurate methods of gfr measurement (i.e. inulin clearance) are expensive and time-consuming and due to limitations of the 24 hour urine collection method, some formula have been developed for the gfr measurement. here we have ...

an agar well diffusion bioassay method for determination of clarithromycin in human plasma, using micrococcus luteus atcc 9341 as the assay organism, was compared with a selective high-performance liquid chromatographic (hplc) method with uv detection. spiked plasma was used to prepare standard and control samples for both methods. the results of the bioassay analyses with spiked plasma samples...

BACKGROUND The determination of Intraepidermal Nerve Fiber Density (IENFD) in skin biopsy is a useful method for the evaluation of different types of peripheral neuropathies. To allow a reliable use of the method it is necessary to determine interobserver reliability. Previous studies dealing with this topic used limited suitable statistical methods. METHODS In the present study three observe...

AIMS A standard approach in test evaluation is to compare results of the assay in validation to results from previously validated methods. For quantitative molecular diagnostic assays, comparison of test values is often performed using simple linear regression and the coefficient of determination (R2), using R2 as the primary metric of assay agreement. However, the use of R2 alone does not adeq...

Abstract Funding Acknowledgements Type of funding sources: Public Institution(s). Main source(s): National Institute for Health Research, UK University Leeds Background Cardiac magnetic resonance (CMR) examinations requiring repeated breath-holds are challenging in younger patients. While 4-dimensional phase-contrast (4D flow) CMR does not require breath-holds, acquisition has been lengthy. The...

Objective: The primary aim of this study was measure and compare the axial length (AXL), keratometric indices (K1, K2) anterior chamber depth (ACD) by biometric devices; IOL Master OB 820, to seek evidence on level agreement for these parameters between two devices.
 Study Design: Quasi-experimental study.
 Place Duration Study: Armed Forces Institute Ophthalmology, Rawalpindi Pakista...

Cardiotocography (CTG) is the widely used cost-effective, non-invasive technique to monitor fetal heart and mother’s uterine contraction pressure assess wellbeing of fetus. The most important parameters baseline upon which other viz. acceleration, deceleration variability depend. Accurate classification into either normal, bradycardia or tachycardia thus fetal-health. Since visual estimation ha...

background preference weights for eq-5d-3l based on visual analogue scale (vas) has recently been developed in iran. the aim of the current study was to compare performance of this value set against the uk vas-based value set.   methods the mean scores for all possible 243 health states were compared using student t test. absolute agreement and consistency were investigated using concordance co...