This chapter reviews the latest research on bisphenol A (BPA), including human exposure, discussions of biomonitoring studies, and toxickinetic models, human health effects and research needs, and experimental studies on low dose effects on the reproductive, neurodevelopmental, and metabolic systems. While the objective here is not to conduct a risk assessment nor directly inform public policy,...

Various adverse effects of endocrine disruptors on the reproductive organs of male animals have been reported. We found that UDP-glucuronosyltransferase (UGT) activities towards bisphenol A, testosterone and oestradiol were significantly decreased in liver microsomes prepared from adult male Wistar rats administered with the endocrine disruptor bisphenol A (1 mg/2 days for 2 or 4 weeks). Howeve...

Bisphenol A is an industrial chemical widely used in plastic products with a consequent exposure to humans. To assess whether exposure to bisphenol A is associated with renal disease, we searched for low-grade albuminuria in 3055 Chinese adults in the Shanghai metropolitan area aged 40 years or older. Using a value for urinary albumin-to-creatinine ratios <30 mg/g, we examined its association w...

The purpose of our study was, to explore the possible ameliorating effects of black tea extract and quercetin, against bisphenol A-induced cytotoxicity. For this, human red blood corpuscles (RBC) were taken as the model. Blood samples collected in EDTA vials from healthy adults were used for preparation of RBC suspension. This suspension was treated with bisphenol A (0-150 microg/mL) with and w...

this study was conducted to reveal the estrogenic effects of bisphenol a and o, p’-ddt on quailembryos. thirteen fertilized eggs were used as control (injected with 20 μl corn oil), 15 eggs were injectedwith estradiol 17β (0.04 mg dissolved in 20 μl corn oil), 20 eggs were injected with bpa (2 mg dissolved in20 μl corn oil) and 20 eggs were injected with o, p’-ddt (2 mg dissolved in 20 μl corn ...

Endocrine-disrupting chemicals are substances present in the environment that can interfere with normal hormonal balance and thus exert potentially adverse health effects on the human organism. Male reproductive system development and function may be susceptible to the effects of such environmental toxicants. Bisphenol A, phthalates and alkylphenols are important components of multiple products...

Thermal and hydrothermal biochars were characterized, and adsorption of bisphenol A (BPA), 17α-ethinyl estradiol (EE2) and phenanthrene (Phen) was determined to investigate the sorption characteristic difference between the two types of biochars. Thermal biochars were composed mostly of aromatic moieties, with low H/C and O/C ratios as compared to hydrothermal ones having diverse functional gro...

Bisphenol A (BPA) is a chemical used extensively to manufacture commonly used plastics and epoxy resin liners for food and beverage cans. BPA, with properties similar to diethylstilbestrol, has been shown to exert endocrine-disrupting effects and result in behavioral changes, altered growth, and early secondary sexual maturation. In 2008, legislation was introduced at the state and federal leve...