Material and methods Since October of 2012, when our outpatient clinic transitioned to an EHR, we implemented the AUDIT and DAST-10 questionnaires as Epic SmartPhrases. A high score on either questionnaire prompts a “brief intervention” (BI), which includes offering the patient a printed brochure. To our SmartPhrases, we added hyperlinks (to http://www.sbirtonline.org and http://www.drugabuse.g...

I N this issue of ANESTHESIOLOGY, Kertai et al. 1 report on the association between anesthetic depth, as measured electroencephalographically with a bispectral index (BIS) monitor, and long-term mortality. It is the fifth observational study on a continuing controversy, which began in 2005 with a paper by Monk et al. We will try to pick up the pieces here. Nonrandomized studies have indicated p...

The synthesis of some 9,10-disubstituted anthracene derivatives are described. 9,10-Bis(2-bromoethyl) anthracene 4,9,10-Bis (2-cyanoethyl) anthracene 5 and 9,10-Bis (4-hydroxybutyl) anthracene 11 are synthesized for the first time.

The aim of this study was to examine the influence of propensity to risk taking, impulsivity, and present versus future orientation in decisionmaking under ambiguity. One hundred and four healthy adults were administered the computer versions of the Iowa Gambling Task (IGT) and the Balloon Analogue Risk Task (BART). They then completed the Barratt Impulsiveness Scale (BIS-11) and the Considerat...

The electrophysiological correlates of error processing were investigated in patients with borderline personality disorder (BPD) using event-related potentials (ERP). Twelve patients with BPD and 12 healthy controls were additionally rated with the Barratt impulsiveness scale (BIS-10). Participants performed a Go/Nogo task while a 64 channel EEG was recorded. Three ERP components were of specia...

A hypothesis suggests that objects with a high degree of visual similarity to real humans trigger negative impressions (i.e., the uncanny valley). Previous studies have suggested that difficulty in object categorization elicits negative emotional reactions to enable the avoidance of potential threats. The present study further investigated this categorization-difficulty hypothesis. In an experi...

in this work, a green, simple and highly efficient procedure for the synthesis of bis(indolyl)methanes is described. the condensation of indoles with carbonyl compounds catalyzed by citric acid in water affords bis(indolyl)methanes in high yields and relatively short reaction times. the advantages of this method are using of water as a low cost solvent and efficient recyclability of the catalyst.

2,2'-Disubstitutedamino-4-4'-bis-pyrimidines (3a-m) have been prepared by linking 2,4-dichloro-6-methyl-5-nitropyrimidine (1) with several diamines and subsequent reaction with suitable amines. Some of these compounds (3c and 3j) which were reduced catalitically, on treatment with nitrous acid, urea in pyridine, and boiling thionyl chloride gave the corresponding bistriazolopyrimidin (6), ...