Production of propionic acid by Propionibacterium shermanii CDB 10014 was enhanced by a pH value of 6.5 and by temperatures in the range 35-37 °C. Depending on the type of yeast extract, succinic acid can be produced in higher proportions, with decreasing propionic acid yields. With respect to propionic acid production, Difco yeast extract has shown the best results when yeast extract preparati...

Benzotriazole-mediated syntheses led to novel bis-conjugates of quinine with quinolone antibiotics and amino acid linkers which were successfully prepared by two alternative routes with excellent yields and retention of chirality. These bis conjugates retain in vitro antimalarial activity with IC(50) values ranging from 12 to 207 nM, similar to quinine itself.

Fermentation of dietary fibers by colonic microbiota generates short-chain fatty acids (SCFAs), e.g., propionic acid and butyric acid, which have been described to have "anti-obesity properties" by ameliorating fasting glycaemia, body weight and insulin tolerance in animal models. In the present study, we therefore investigate if propionic acid and butyric acid have effects on lipolysis, de nov...

The evidence for this scheme is : (a ) Washed suspensions of the organism grown on lactate attack, under anaerobic conditions, pyruvate, oxalacetate, L-malate, fumarate and succinate, but not D-tartrate. (b) Organisms grown on D-tartrate attack it and all the substances listed in (a ) except lactate. ( c ) Succinic acid is quantitatively decarboxylated to propionic acid and carbon dioxide. (d )...

New mixed-substituent amino/carboxyphenylporphyrins for a dye-sensitized TiO2 solar cell were prepared using several synthetic routes. The reaction of 4-carbomethoxyand 4-acetamidobenzaldehydes with pyrrole in propionic acid under aerobic conditions afforded mixtures of mixed amide/ester substituted tetraphenylporphyrins which were separated using centrifugal chromatography then deprotected to ...

Earlier there was found activity of glutamatergic ionotropic α-amino-3-hydroxy-5-methylisoxazole-4-propionic acid (AMPAR) and N-methyl-D-aspartate receptors (NMDAR) disturbed after prolonged cryopreservation brain slices at temperature -10 оС. To eliminate cryodamage AMPAR NMDAR, the were encapsulated in special freezing solution (SFS). SFS consisted agar various concentrations (33, 44 50 %) ar...

BACKGROUND Dietary fibre is fermented by the colonic microbiota to carboxylic acids (CA), with potential health effects associated in particular with butyric and propionic acid. OBJECTIVE To investigate the formation of CA in the hindgut of healthy rats fed dietary fibre from different fractions of wheat shorts, a by-product of the milling of wheat. DESIGN Rats were fed dietary fibre (80 g/...