Five polychlorinated biphenyl (PCB)-degrading bacteria were tested for the ability to differentiate between the enantiomers of four atropisomeric PCB congeners (2,2',3,6-tetra-CB; 2,2',3,3',6-penta-CB; 2,2',3,4',6-penta-CB; and 2,2',3,5',6-penta-CB) after growth in the presence of tryptone-soytone, biphenyl, carvone, or cymene. Enantioselectivity was shown to vary with respect to strain, congen...

Exposure of isolated hepatocytes to a polychlorinated biphenyl mixture induced a rapid loss of cell viability. The effect was not dose-dependent. The biochemical effects in the cellular toxicity did not involve glutathione content, protein sulfhydryl groups and lipid peroxidation. A transient increase in cytosolic Ca2+ was observed after exposing the hepatocytes to the polychlorinated biphenyl ...

The polychlorinated biphenyl congener 2,3,4,5,6-pentachlorobiphenyl and hexachlorobenzene were reductively dechlorinated in an aqueous biomimetic model system containing vitamin B12. The products of 2,3,4,5,6-pentachlorobiphenyl dechlorination were 2,3,5,6- and 2,3,4,6-tetrachlorobiphenyl. Hexachlorobenzene dechlorinated to pentachlorobenzene and a mixture of 1,2,4,5- and 1,2,3,5-tetrachloroben...

Both monoand bisylide zwitterionic complexes of gold(I), [(C6F5){PhCH(PPh3)}Au] (4), [(C6F5)2(C6H4-p){CH(PPh3)}2Au2] (5) and [(C6F5)2(C6H4-m){CH(PPh3)}2Au2] (6) were prepared by THT substitution in [C6F5(THT)Au] (THT = tetrahydrothiophene) using deprotonated monoand bis-phosphonium salts. Lithiation of 4,4′-dibromo-2,3,5,6,2′ ,3′,5′,6′-octafluoro-1,1′biphenyl and transmetallation with [Cl(Ph3P)...

An anaerobic culture capable of dechlorinating polychlorinated biphenyls was subcultured under strict anaerobic conditions on solid media containing sterilized river sediment. The dechlorination activity was transferred as a bacterial colony on a solid medium three times. After two transfers on solid medium, the culture was no longer methanogenic but still dechlorinated a mixture of tri- and te...

The influence of electron donors and electron acceptors of variable strength in the 4 and 4' position of 2 and 2' propyl-bridged axial chiral biphenyl cyclophanes on their atropisomerization process was studied. Estimated free energies ΔG(‡)(T) of the rotation around the central biphenyl bond which were obtained from (1)H-NMR coalescence measurements were correlated to the Hammett parameters σ(...

To improve the capabilities of microorganisms relevant for biodegradation, we developed a new genetic approach and applied it to the bph operon (bphEGF[orf4]A1A2A3CD[orf1]A4R) of Pseudomonas sp. strain KKS102 to enhance its biphenyl- and polychlorinated biphenyl (PCB)-degrading activity. A native promoter of the bph operon, which was under control, was replaced through homologous recombination ...

Spectacular progress has recently been achieved in transition metal-catalyzed C−H borylation of phosphines as well directed electrophilic borylation. As shown here, P-directed provides a new, straightforward, and efficient access to phosphine–boranes. It operates under metal-free conditions leverages simple, readily available substrates. is applicable broad range backbones (naphthyl, biphenyl, ...