biological analysis

Ahmad Fazeli, Ali Mohammadi, Hosein Rastegar, Mahmoud Alebouyeh, Mohammad Reza Fazeli, Mohammad Reza Khoshayand, Sameereh Hashemi-Najafabadi, Tahereh Babaee,

Recombinant plasminogen activator (reteplase) is a third generation thrombolytic agent which has been used on coronary artery thrombosis and acute myocardial infarction. Clot lysis assay is usually considered as a unique method to evaluate biological activity of reteplase. In this study biological activity of reteplase was determined by APTT (activated partial thromboplastin time) lysis method....

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Determination of Biological Activity of Recombinant Reteplase Using Clot Lysis Time and Activated Partial Thromboplastin Time (APTT) Lysis Methods: A Comparative Study

Journal: The Iranian Journal of Pharmaceutical Research 2018

Ahmad Fazeli, Ali Mohammadi, Hosein Rastegar, Mahmoud Alebouyeh, Mohammad Reza Fazeli, Mohammad Reza Khoshayand, Sameereh Hashemi-Najafabadi, Tahereh Babaee,

Recombinant plasminogen activator (reteplase) is a third generation thrombolytic agent which has been used on coronary artery thrombosis and acute myocardial infarction. Clot lysis assay is usually considered as a unique method to evaluate biological activity of reteplase. In this study biological activity of reteplase was determined by APTT (activated partial thromboplastin time) lysis method....

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