DNA intercalators belong to aromatic heterocyclic compounds interacting reversibly with DNA. These compounds have been used extremely as cytotoxic agents against cancer. In this study, the synthesis and biological activity of some novel derivatives of cyclopenta [b] quinoline-1, 8-dione as new intercalating agent were investigated. Twenty novel derivatives of cyclopenta [b] quinoline-1, 8-dione...

this study aimed to determine biological activity and phytochemical study of scutellaria platystegia (family labiatae). methanolic (meoh) extract of aerial parts of s. platystegia and spe fractions of methanolic extract (specially 20% and 40% methanolic fractions), growing in east-azarbaijan province of iran were found to have radical scavenging activity by dpph (2, 2-diphenyl -1- pycryl hydraz...

Ingredients in Aloe Vera Gel Mannose and glucose are the most significant sugars found in the Aloe vera gel, and they can be used to assay the activity of Aloe vera. The gel contains important sterols which can have anti-inflammatory activity. Amino acids such as tryptophane and phenylaianine reduce inflammation. Studies have shown that vitamin C & B complex can maintain adrenalectomized animal...

The hypothesis that uncoupling protein 3 (UCP3) is an uncoupling protein involved in heat dissipation is not unequivocally supported. An update of in vitro, ex vivo and in vivo studies testing this hypothesis is presented. Data are provided showing that exercise induces a fatty acid-dependent increase in muscle UCP3 mRNA in humans. The proposed positive correlation between glycolytic capacity a...

The toxicity of alfatoxin B(2a) (hydroxydihydro-aflatoxin B(1)) was studied in several biological systems. Aflatoxin B(2a) is the monohydroxylated derivative obtained from addition of water to the double bond of the terminal furan of B(1). Examination of the sensitivity of a group of microorganisms to B(2a) demonstrated that the inhibitory spectrum was similar to aflatoxin B(1). However, the to...

bipolaris oryzae causes rice brown spot disease which reduces rice yield with substantial global impact. streptomycetes isolated from rice fields of guilan province, iran, showed antifungal activity against the tested pathogen. from five active streptomyces spp. isolates, isolate g showed high antagonistic activity. to determine its taxonomical identity, its colonies characterized morphological...