We believe that a significant improvement in health and a decrease in the age-specific morbidity and mortality from various diseases can be achieved by varying the concentrations in the body of the molecules that are normally present, many of which are required for life (1). The corresponding field is described as “orthomolecular medicine.” An important part of orthomolecular medicine, orthomol...

Radix Aconiti, a classic traditional Chinese medicine (TCM), has been widely used throughout China for disease treatment due to its various pharmacological activities, such as anti-inflammatory, cardiotonic, and analgesic effects. However, improper use of Radix Aconiti often generated severe acute toxicity. Currently, research on the toxic substances of Radix Aconiti is not rare. In our previou...

In January 2014, an industrial storage tank containing multiple coal processing chemicals ruptured and spilled approximately 37,850 liters of Crude MCHM and polyglycol ethers into the Elk River in West Virginia. This environmental disaster polluted drinking water for more than 300,000 residents, many of whom were pregnant women, infants, and children. These substances cause eye/skin irritation ...

A rat model of cerebral hemorrhage using stereotaxic injection of blood into the right basal ganglia was developed to investigate the influence of iron metabolism on the appearance of cerebral hemorrhage on MR images. Images of in vitro fixed brain sections stained specifically for different iron-storage substances, ferritin and hemosiderin, created by digitization of the pathology sections usi...

Abstract Lonicera edulis L. occupies a special place among sparsely distributed garden crops in the middle horticulture zone of Russia. The main advantages culture are its long maturation period, fruiting high plasticity, value biochemical composition berries. paper presents experimental data on honeysuckle berries new generation introduced under conditions Central Chernozem Region. Varieties w...

Several chemical substances belonging to classes of natural dietary origin display protective properties against some age-related diseases including neurodegenerative ones, particularly Alzheimer's disease (AD). These compounds, known as nutraceuticals, differ structurally, act therefore at different biochemical and metabolic levels and have shown different types of neuroprotective properties. ...

The physiological role of microbial surfactants production in microorganisms includes antimicrobial activity and break down of complex hydrocarbon substances to make the substrates readily available for uptake in adverse environmental conditions. Wax degrading bacteria are a significant group of microorganisms facilitated mainly by the production of microbial surfactants to emulsify waxy substa...

A CHARACTERISTC of biochemistry is its great heritage of colour tests which have been devised to meet the demand for means of identifying substances of complex or unknown constitution where the more exact methods of pure organic chemistry were of no avail. Some of these biochemical tests are of a degree of delicacy and specificity almost comparable to biological reactions; but, owing to the dif...

Pesticides are used to protect plants all over the world. Their increasing specificity has been due to utilization of differences in biochemical processes, and has been accompanied by lower human toxicity. Nevertheless cases of poisoning are still observed. While certain toxic substances are provided with characteristic dyes or pigments to facilitate easy identification, no overview of pesticid...

This report presents an overview of the patterns of liver injury produced by presently recognized toxic substances in the environment. Current concepts of the metabolic disposition of these substances in the liver suggest that their toxic effects may be modulated by an interplay between enzymatic pathways for activation or inactivation of foreign compounds. A better understanding of the genetic...