Background and objective: The fitting of orthokeratology (ortho-k) multifocal soft contact lenses (SCL) is becoming increasingly popular worldwide for reducing the rate myopia progression. However, overnight wear use microbial contamination storage vials has been shown to increase risk corneal inflammatory infiltrative events (CIEs). Therefore, we conducted a pilot study compare rate, level, ty...

LEVEL: INTERMEDIATE U nder ideal conditions, the result of a sterility test reflects the presence or absence of viable organisms in the samples analyzed. However, it has long been recognized that inferences regarding sterility (whether for a batch of inprocess material or a finished dosage form) are subject to statistical limitations. The probability (P) of detecting contamination in a given ba...

BACKGROUND Purified water for pharmaceutical purposes must be free of microbial contamination and pyrogens. Even with the additional sanitary and disinfecting treatments applied to the system (sequential operational stages), Pseudomonas aeruginosa, Pseudomonas fluorescens, Pseudomonas alcaligenes, Pseudomonas picketti, Flavobacterium aureum, Acinetobacter lowffi and Pseudomonas diminuta were is...

BACKGROUND The objective of this study was to perform simulated-use testing as well as a clinical study to assess the efficacy of the EVOTECH Endoscope Cleaner and Reprocessor (ECR) cleaning for flexible colonoscopes, duodenoscopes, gastroscopes and bronchoscopes. The main aim was to determine if the cleaning achieved using the ECR was at least equivalent to that achieved using optimal manual c...

There are so many ISO documents to understand and utilize for validation studies and routine control. A biological indicator (BI) is essential for conducting sterilization validation and routine control. ISO 11138-1 and ISO 14161 are the major documents to follow for BI manufacturers and BI users, respectively. In ISO 11138-1, BI manufacturers must utilize a BI with 106 CFU/carrier as an initia...

In questo articolo si discute il caso controllo di una medicazione composta da Rigenase© (stimolina origina vegetale) addizionata poliesanide, su un nuovo supporto in PET triplo strato nel trattamento lesioni cutanee croniche dell’arto inferiore. Scopo dello studio è la valutazione termini riparazione e del bioburden Batterico. Sono stati arruolati 20 pazienti con periodo run 6 settimane terapi...

This study aims to assess the airborne bioburden of rural and urban Portuguese Primary Health Care Centers (PHCC) using active passive sampling methods identify potential differences in microbiota between both environments. The highest total aerobic mesophilic bacterial load indoor air were found Vaccination Room (448 CFU.m?3) Rural PHCC Waiting (420 for Urban PHCC. coliforms contamination leve...

•Dry Hydrogen Peroxide reduces environmental contamination in air and on surfaces.•Dry is safe for use occupied settings, human exposure.•No-touch disinfection technology effective adjunct to manual cleaning.•Dry shown be no-touch technology.•Hospital achieves continuous with Dry Peroxide. BackgroundRoutine cleaning of the health care environment often suboptimal. Residual poses an infection ri...