Multiple components of broccoli, such as sulforaphane (Sf) and phenolic acids, may inhibit cancer. Additionally, broccoli can accumulate selenium (Se), and Se has been demonstrated to reduce the risk of cancer. Studies were conducted to determine whether enhancement of broccoli with Se would produce a plant with superior health benefits. Although increasing the concentration of Se in broccoli f...

In recent years, due to vital need for novel fungicidal agents, investigation on natural antifungal resources has been increased. The special features exhibited by neural network classifiers make them suitable for handling complex problems like analyzing different properties of candidate compounds in computer-aided drug design. In this study, by using a Levenberg-Marquardt (LM) neural network (...

The complex nature of in vivo gene transfer establishes the need for multifunctional delivery vectors capable of meeting these challenges. An additional consideration for clinical translation of synthetic delivery formulations is reproducibility and scale-up of materials. In this review, we summarize our work over the last five years in developing a modular approach for synthesizing peptide-bas...

Cholesterol, fatty acids, fat-soluble vitamins, and other lipids present in our diets are not only nutritionally important but serve as precursors for ligands that bind to receptors in the nucleus. To become biologically active, these lipids must first be absorbed by the intestine and transformed by metabolic enzymes before they are delivered to their sites of action in the body. Ultimately, th...

Bioactive glasses release ions such as sodium when implanted in the human body. However, an excess of released can cause problems related to cytotoxicity. The ion control is considered one primary challenges developing new bioactive glasses. Here, we use molecular dynamics simulations investigate effect density on atoms’ archetypal phosphosilicate system. diffusion coefficient displays three ma...

Nano Bioactive glass material of the type CaO–P2O5–SiO2 was obtained by the sol-gel processing method at considerably lower temperatures than required for conventional melting methods. As a new modification, volume of solution was changed in order to investigate its effects on the properties of bioglass samples. The obtained material was characterized by X-ray powder diffraction (XRD), surface ...