I nterest in fluctuating asymmetry, FA (Box l), has recently spread across diverse disciplines in the life sciences, including medicine, genetics, conservation and developmental biology, and behavioral ecologysl. FA allows researchers to evaluate a basic aspect of viability fitness, namely, developmental stability the capacity to develop properly in the face of genetic and environmental stresse...

Even before the deep brain stimulation (DBS) era, stereotactic functional neurosurgery such as thalamotomy and pallidotomy had been used for control of medically intractable dystonia (Cooper, 1976; Lozano et al., 1997). However, unreliability and variability in the results and furthermore, needs for bilateral surgery in most patients with generalized dystonia and the occurrence of unacceptable ...

Two- or 100-Hz electrical acupoint stimulation (EAS) can induce analgesia via distinct central mechanisms. It has long been known that the extent of EAS analgesia showed tremendous difference among subjects. Functional MRI (fMRI) studies were performed to allocate the possible mechanisms underlying the frequency specificity as well as individual variability of EAS analgesia. In either frequenci...

Bilateral cochlear implants (CIs) have provided some success in improving spatial hearing abilities to patients, but with large variability in performance. One reason for the variability is that there may be a mismatch in the place-of-stimulation arising from electrode arrays being inserted at different depths in each cochlea. Goupell et al. [(2013b). J. Acoust. Soc. Am. 133(4), 2272-2287] show...

BACKGROUND Essential tremor (ET) is one of the most common hyperkinetic movement disorders. Previous research into the pathophysiology of ET suggested underlying cerebellar abnormalities. OBJECTIVE In this study, we added electromyography as an index of tremor intensity to functional Magnetic Resonance Imaging (EMG-fMRI) to study a group of ET patients selected according to strict criteria to...

abstract   introduction: it is demonstrated that the degree of clinical improvement in   parkinson's disease (pd) achieved by deep brain stimulation (dbs) is largely dependent   on the accuracy of lead placement. in addition, individual variability in the   situation of subthalamic nucleus (stn) is responsible for spatial inter-individual   fluctuations of the real patient's target.  ...

The Mongolian gerbil (Meriones unguiculatus) has been used extensively as a model of forebrain ischemia. Its unique susceptibility to ischemia was suggested to be due to an incomplete circle of Willis. The relative ease to which ischemia can be induced combined with highly reproducible delayed CA1 cell death following a 5 min occlusion made the model popular in neuroprotection studies. Presentl...

The neurophysiological basis of variability in the latency of evoked neural responses has been of interest for decades. We describe a method to identify white matter pathways that may contribute to inter-individual variability in the timing of neural activity. We investigated the relation of the latency of peak visual responses in occipital cortex as measured by magnetoencephalography (MEG) to ...