نتایج جستجو برای: bi

تعداد نتایج: 46273  

Journal: :iranian journal of science and technology (sciences) 2013
t. mahmood

in this paper we define ( , ) k  q -fuzzy h -sub hemirings, ( , ) k  q -fuzzy h -ideals, ( , ) k  q - fuzzy     h -bi-ideals and ( , ) k  q -fuzzy h -quasi-ideals. we characterize h -hemiregular and h -intrahemiregular hemirings by the properties of their     ( , ) k  q -fuzzy h -ideals, ( , ) k  q -fuzzy h -bi-ideals and     ( , ) k  q -fuzzy h -quasi-...

2002
Courtney Darves Sharon L. Oviatt

The design of robust new interfaces that process conversational speech is a challenging research direction largely because users’ spoken language is so variable, which is especially true of children. The present research explored whether children’s response latencies before initiating a conversational turn converge with those heard in the text-to-speech (TTS) of a computer partner. A study was ...

Journal: :Chemical communications 2014
Takahiro Iwasaki Tetsuya Kato Yoichi Kobayashi Jiro Abe

We developed a chiral 1,1'-bi-2-naphthol-bridged imidazole dimer possessing 100 μs fast photochromism and high fatigue resistance. It offers great opportunities for the practical applications to fast photoresponsive chiral dopants, invisible security materials and optical trigger molecules to induce the dynamic structural changes in biological matters.

2014
Pietro Ciceri Susanne Müller Alison O'Mahony Oleg Fedorov Panagis Filippakopoulos Jeremy P Hunt Elisabeth A Lasater Gabriel Pallares Sarah Picaud Christopher Wells Sarah Martin Lisa M Wodicka Neil P Shah Daniel K Treiber Stefan Knapp

Concomitant inhibition of multiple cancer-driving kinases is an established strategy to improve the durability of clinical responses to targeted therapies. The difficulty of discovering kinase inhibitors with an appropriate multitarget profile has, however, necessitated the application of combination therapies, which can pose major clinical development challenges. Epigenetic reader domains of t...

2001
Iraj Mohammadpoor-Baltork Ahmad R. Khosropour

Various epoxides are converted to their corresponding thiiranes in excellent yields with ammonium thiocyanate and thiourea under non-aqueous conditions in the presence of catalytic amounts of Bi(TFA)3 and Bi(OTf)3.

2010
Noelia Vállez Gloria Bueno García Oscar Déniz-Suárez Pablo Esteve Miguel A. Rienda Carlos Pastor

Introduction Breast cancer continues to be an important health problem. Early detection is needed to improve prognosis and significantly reduce women mortality. Computer-Aided Diagnosis systems (CAD) can help radiologist to improve their ability to detect and classify breast lesions. However, automated interpretation of mammogram lesions still remains very difficult. Some of the reasons are the...

Journal: :Journal of lipid research 2006
May Brundert Joerg Heeren Mukaddes Bahar-Bayansar Anne Ewert Kathryn J Moore Franz Rinninger

Scavenger receptor class B type I (SR-BI) mediates the selective uptake of HDL cholesteryl esters (CEs) and facilitates the efflux of unesterified cholesterol. SR-BI expression in macrophages presumably plays a role in atherosclerosis. The role of SR-BI for selective CE uptake and cholesterol efflux in macrophages was explored. Macrophages and HDL originated from wild-type (WT) or SR-BI knockou...

Journal: :CoRR 2017
Michal Byra Katarzyna Dobruch-Sobczak Hanna Piotrzkowska-Wróblewska Andrzej Nowicki

Ultrasound imaging plays an important role in breast lesion differentiation. However, diagnostic accuracy depends on ultrasonographer experience. Various computer aided diagnosis systems has been developed to improve breast cancer detection and reduce the number of unnecessary biopsies. In this study, our aim was to improve breast lesion classification based on the BI-RADS (Breast Imaging Repor...

Journal: :Cell host & microbe 2008
Samir Yalaoui Thierry Huby Jean-François Franetich Audrey Gego Armelle Rametti Martine Moreau Xavier Collet Anthony Siau Geert-Jan van Gemert Robert W Sauerwein Adrian J F Luty Jean-Christophe Vaillant Laurent Hannoun John Chapman Dominique Mazier Patrick Froissard

Infection of hepatocytes by Plasmodium falciparum sporozoites requires the host tetraspanin CD81. CD81 is also predicted to be a coreceptor, along with scavenger receptor BI (SR-BI), for hepatitis C virus. Using SR-BI-knockout, SR-BI-hypomorphic and SR-BI-transgenic primary hepatocytes, as well as specific SR-BI-blocking antibodies, we demonstrate that SR-BI significantly boosts hepatocyte perm...

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