The gold standard for assessing quality of forced expiratory manoeuvres is visual inspection by an expert. American Thoracic Society/European Respiratory Society numerical quality criteria (NQC) include back-extrapolated volume (BEV), repeatability and forced expiratory time (FET). Equipment currently available provides feedback tempting the investigator to use NQC as pass-fail criterion. To in...

The aim of this study was to assess the activity and safety of bevacizumab (BEV) and fotemustine (FTM) for the treatment of recurrent glioblastoma multiforme (GBM) patients and explore the potential prognostic parameters on survival. This study retrospectively analyzed all patients with GBM who were treated with at least one cycle of BEV and FTM from July 2010 to October 2012. A total of 176 pa...

Different chemotherapy drugs are generally introduced in clinical practices combining with therapy for glioma treatment. However, these chemotherapy drugs have rarely been compared with each other and the optimum drug still remains to be proved. In this research, medical databases were consulted, PubMed, Embase and Cochrane Library included. As primary outcomes, hazard ratio (HR) of overall sur...

The prognostic significance of glandular differentiation in urothelial carcinoma (UC) is controversial, and thus far there is no established treatment strategy against metastasis of glandular component. We describe here a case of metastatic UC with glandular differentiation that had histological disappearance of adenocarcinoma components at autopsy after sequential chemotherapy with S-1 and cis...

High Performance (HP) battery electric vehicle (BEV) and racing applications represent significantly different use cases than those associated with conventional consumer vehicles and road driving. The differences between HP use cases and the duty-cycles embodied within established battery test standards will lead to unrepresentative estimates for battery life and performance within a HP applica...

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INTRODUCTION Metal baseball bats produce higher ball exit velocity (BEV) than wood bats, increasing the risk of impact injuries to infield players. In this paper, maximum BEV from a wood and a metal bat were determined using the finite element method. METHODS Three-dimensional (3-D) bat kinematics at the instant of impact were determined from high-speed videography (N = 17 high-performance ba...

It is commonly held that range anxiety, in the form of experienced range stress, constitutes a usage barrier, particularly during the early period of battery electric vehicle (BEV) usage. To better understand factors that play a role in range stress during this critical period of adaptation to limited-range mobility, we examined individual differences in experienced range stress in the context ...

We supplied 25 two-car households with a short-range battery electric vehicle (BEV) to study their adaptation BEV replacing one of conventional cars. The data includes GPS-measured driving the households’ two original cars for 2–3 months, and remaining car 3–4 months. performed interviews before after trial period. can thus compare change in measured patterns users’ experienced relation adaptat...