The enzyme omega-transaminase catalyses the conversion of chiral omega-amines to ketones. The recombinant enzyme from Chromobacterium violaceum has been purified to homogeneity. The enzyme was crystallized from PEG 4000 using the microbatch method. Data were collected to 1.7 A resolution from a crystal belonging to the triclinic space group P1, with unit-cell parameters a = 58.9, b = 61.9, c = ...

Matrix elements of observables in eigenstates generic Hamiltonians are described by the Srednicki ansatz within eigenstate thermalization hypothesis (ETH). We study a quantum chaotic spin-fermion model one-dimensional lattice, which consists spin-1/2 XX chain coupled to single itinerant fermion. In our study, we focus on translationally invariant including charge and energy current, thereby als...

Resumen
 Objetivo: La población geriátrica está aumentando y conocer su salud es necesario a nivel mundial para poder planear políticas públicas que mejoren calidad de vida, la independencia funcional través capacidad hacer actividades diarias básicas un buen indicador necesidad atención médica. Una las escalas más usadas esto esel Índice Barthel, por lo el propósito este trabajo fue valid...

Abstract Propagating guided waves in a homogeneous, isotropic, prestressed, hyperelastic plate show nonlinear characteristics that depend on the state of initial prestress. These phenomena include higher harmonic generation, occurring when Lamb wave modes different frequencies ( $$\omega _a$$ ω a</mml:...

We focus on the random generation of SAT instances that have properties similar to real-world instances. It is known many industrial instances, even with a great number variables, can be solved by clever solver in reasonable amount time. This not possible, general, classical randomly generated provide different model called \emph{scale-free instances}. based use non-uniform probability distribu...

BACKGROUND There is overwhelming evidence that dietary supplementation with n-3 polyunsaturated fatty acids (PUFAs), mainly EPA (C20:5n-3) and DHA (C22:6n-3), has cardiovascular protective effects on patients with type 2 diabetes mellitus (T2DM) but not on healthy people. Because the T2DM heart increases fatty acid oxidation (FAO) to compensate for the diminished utilization of glucose, we hypo...

Evolutionarily divergent proteins have been shown to change their interacting partners. RNA polymerase assembly is one of the rare cases which retain its component proteins in the course of evolution. This ubiquitous molecular assembly, involved in transcription, consists of four core subunits (alpha, beta, betaprime, and omega), which assemble to form the core enzyme. Remarkably, the orientati...

Lewis acidic indium(III) salts, in particular In(NTf(2))(3), effect the conversion of alpha-(omega'-alkynyl)-beta-ketoesters and omega-alkynyl-beta-ketoesters to the corresponding cyclic products in a manner known as the Conia-ene reaction. This reaction can lead to the creation of five- to fifteen-membered-ring carbocycles and heterocycles in good to excellent yields. The synthetic features of...

We previously showed that pancreatic beta-cells express a neuronal isoform of nitric oxide synthase (nNOS) that controls insulin secretion by exerting two enzymatic activities: nitric oxide (NO) production and cytochrome c reductase activity. We now bring evidence that two inhibitors of nNOS, N-omega-nitro-l-arginine methyl ester (l-NAME) and 7-nitroindazole (7-NI), increase glucose-induced ins...