Four derivatives of benzotriazole-5-carboxylic acid were synthesized as potential UV-light dependent DNA cleaving agent. The effect of these compounds on phiX174 RF1 phage DNA and pBR322 plasmid DNA was investigated with and without UV exposure. It has been found that the two compounds exert the influence on topological forms of DNA.

The complete molecule of the title compound, C(24)H(24)N(6)O(2), is generated by a crystallographic inversion centre. The benzotriazole rings form dihedral angles of 2.10 (7)° with the central aromatic ring. The crystal packing is consolidated by π-π inter-actions, with centroid-centroid distances of 3.6234 (10) Å, together with weak C-H⋯π inter-actions.

Convenient and efficient synthesis of a new environmentally sensitive chlorine-substituted 2,3-naphthalimide-based fluorophore is reported. Benzotriazole carboxyl group activation of the 6-chloro-fluorophore enabled quick labeling of free and Fmoc-protected amino acids. The photophysical properties of the compounds obtained include high quantum yields in solvents of different polarity: water, m...

The adsorption of benzotriazole--an outstanding corrosion inhibitor for copper--on Cu(111), Cu(100), Cu(110), and low coordinated defects thereon has been studied and characterized using density functional theory (DFT) calculations. We find that benzotriazole can either chemisorb in an upright geometry or physisorb with the molecular plane being nearly parallel to the surface. While the magnitu...

Benzotriazoles (BZTs) are ubiquitous aquatic contaminants used in a wide range of industrial and domestic applications from aircraft deicers to dishwasher tablets. Acute toxicity has been reported in aquatic organisms for some of the BZTs but their mode of action remains unknown. The objectives of this study were to evaluate the transcriptomic response of D. magna exposed to sublethal doses of ...

In the title complex, [Cd(C13H8N5)2(C2H5OH)2], the Cd(II) cation is located on an inversion center and coordinated by two deprotonated 2-(1H-benzotriazol-1-yl)-1H-benzimid-azol-1-ide (L) ligands and two ethanol mol-ecules in a distorted N4O2 octa-hedral geometry. In the L ligand, the dihedral angle between benzoimidazole and benzotriazole ring systems is 10.8 (3)°. In the crystal, the complex m...

Snowbank samples were collected from snowbanks within a medium-sized airport for four years to characterize aircraft deicer and anti-icer (ADAF) components and toxicity. Concentrations of ADAF components varied with median glycol concentrations from individual sampling periods ranging from 65 to 5940 mg/L. Glycol content in snowbanks ranged from 0.17 to 11.4% of that applied to aircraft. Glycol...

In the title compound, C(22)H(18)N(4)O(4), mol-ecules are linked to each other by C-H⋯N and C-H⋯O inter-molecular hydrogen-bonding inter-actions. The crystal packing is further stabilized by C-H⋯π, and π-π inter-actions with a distance of 3.783 (3) Å between the centroids of the benzene rings of the benzotriazole system.

1-Aryl-1H-benzotriazoles and -1H-indazoles were synthesized, and their deproto-metallation using the base prepared by mixing LiTMP with ZnCl2·TMEDA (1/3 equiv.) was studied. In the indazole series, reactions occurring at the 3 position were followed by ring opening, and functionalization of the substrate was only found possible (on the sulfur ring) using 2-thienyl as aryl group. In the benzotri...

Conjugated copolymers with an alternating donor-acceptor (D-A) architecture are exploited as low-bandgap and high-hole-mobility materials in organic electronics. However, several of the presently available modeling methods predict different geometries and electronic properties for the same copolymer. In this work, the effect of the amount of exact Hartree-Fock (HF) exchange in density functiona...