There is at present considerable interest in the newer forms of penicillin which ha^ been introduced since the isolation of the penicillin nucleus 6-amino penicillanic in 1959 made possible, by substitution of differing side chains, the production of 3 whole range of new penicillin compounds. This trial was designed to compare the clinical effectiveness of two of these, phenethicillin and propi...

penicillin g acylase from e. coli ta1 was immobilized by cross-linked enzyme aggregates (clea), a new method for immobilization. this biocatalyst and commercial immobilized penicillin g acylase (pga-450) were used to study the effect of ph, temperature and substrate concentration on the synthesis of ampicillin from phenyl glycine methyl ester (pgme) and 6-aminopenicillanic acid (6-apa). compare...

in this paper, the effect of penicillin g drug as a green corrosion inhibitor on mild steel in 1.0 mhydrochloric acid solution has been investigated using potentiodynamic polarization, electrochemicalimpedance spectroscopy (eis) and electrochemical noise (en) techniques. the inhibition efficiencywas found to increase with increasing inhibitor concentration. potentiodynamic polarizationmeasureme...

The in vitro activity of combinations of penicillin and netilimicin was determined against 20 clinical isolates of enterococci and compared with that obtained in simultaneous tests with penicillin/sisomicin, penicillin/streptomycin, and penicillin/kanamycin. Synergy between the two drugs in each combination was determined by the use of quantitative kill curves and was defined as a killing by th...

When penicillin was added to cultures of Mycoplasma neurolyticum in amounts up to 1,000 units per ml, lag time and generation time were increased and the total population was reduced in proportion to the antibiotic concentration. Although growth suppression by penicillin was complete, the death rate was slow and linear over periods up to 12 days. Growth after induced lag was due to a decay in p...

Penicillin allergy is the most commonly reported drug allergy in the United States. However, after undergoing a complete evaluation by a board-certified allergist, including skin testing, 90% of patients labeled as 'penicillin-allergic' are able to tolerate penicillin. Clinical presentation is key in classifying reactions as either mediated by or not mediated by immunoglobulin E (IgE), and in d...

Background Penicillin allergy is a major concern among patients and physicians. There’s an estimated 5-10% self reported history of penicillin allergy by patients, but vast majority are not true hypersensitivities. Complete penicillin skin test with both major, minor determinants and amoxicillin is the test of choice for diagnosing IgE-mediated penicillin allergy. While Penicilloyl polylysine (...

The antibacterial activities of a number of amide derivatives of penicillin against both penicillin-sensitive and penicillin-resistant cultures were determined. Several of them were found to possess significant inhibitory activity against certain gram-positive bacteria. The amides, although resistant to the destructive action of beta-lactamase, did not protect G in competitive experiments. One ...