Aim: The aim of the present study was to design and evaluate solid lipid nanoparticles Asenapine maleate (<2% bioavailability) enhance its oral bioavailability surface modification for brain targeting.
 Methods: A modified solvent injection method used produce loaded nanoparticles. RSM 3-factor, 3-level Box-Behnken applied effect three independent variables, concentrations (A), drug (B)...

Objective: The purpose of the present study is to develop, statistically optimize and evaluate transfersomal gel formulation Tofacitinib citrate via transdermal route by DOE Approach. Materials Methods: Transferosomes are made up with bilayer forming phospholipids biocompatible surfactants like sodium deoxycholate. also acts as edge activator which stabilizes phospholipid increases deformabilit...