Behcet’s Disease (BD) is a multisystem inflammatory disorder of chronic course, highly frequent in certain ethnic groups (Turks, Israelis, Oriental). Although the disease is considered of low prevalence in children, recent registries indicates an increase in disease recognition. It characterizes by a broad spectrum of clinical manifestations, including ocular, musculoskeletal, CNS, gastrointest...

Adamantiades-Behcet disease (ABD) is a multisystemic, chronic inflammatory disorder of unknown etiology with diffuse clinical manifestations including those involving the cardiovascular system. While the disease is most prevalent in the Mediterranean region, the Middle East and the Far East, its prevalence is increasing in Western countries due to migration patterns. Cardiovascular involvement ...

Behcet disease is a rare multi-system immune related vasculitis which may involve the central nervous system, usually during the course of the illness. Magnetic resonance imaging is currently the modality of choice for the detection of the parenchymal lesions in their different phases, as well as the dural sinus venous thrombosis.

background: the prevalence of anti-neutrophil cytoplasmic antibodies (ancas) and anti-cardiolipin antibodies (anti-cl ab) in behcet’s disease (bd) and also their roles in vascular involvement is controversial. objective: to assess the prevalence of ancas and anti-cl ab as well as their correlations with clinical manifestations in iranian patients with bd. methods: in this case/control study, th...

background: behçet’s disease (bd) is a multisystemic inflammatory vasculitis of unknown etiology, and vasculitis being its major pathological feature. objectives: we studied the prevalence of microembolic signals (mes) in patients with diagnosis behçet's disease. we also tried to determine the frequency of mes in bd patients with or without neurological involvement. materials and methods: ...

Behçet disease is a systemic disease with diverse clinical symptoms which include, but not limited to, patients having oral and genital ulcers and eye involvement. We here report an 18-year-old male presenting with massive hemoptysis and cardiac arrest, having history of ulcers in the oral cavity and genitalia as well as having recent episode of uveitis. A pulmonary CT angiography revealed bila...

Intercellular adhesion molecule-1 (ICAM-1) is expressed on vascular endothelial cells and its expression increases during the inflammatory response in patients with active Behcet's disease (BD). The ICAM1 gene mutations are associated with BD in Caucasians, but clinical features of the mutation phenotype are unknown. We analyzed ICAM1 polymorphisms in Korean BD patients to determine if there wa...

Behcet disease (BD), a vasculitic disease, may present with a broad range of systemic manifestations. Urologic complications are rarely described in the literature, but when they occur, they present as epididymo-orchitis. We describe a rare case of testicular infarction in a patient with BD followed up with serial ultrasound imaging. We highlight the diagnostic challenges when presented with te...

BACKGROUND A relapsing systemic inflammatory process is a well-known feature of Behcet's disease. Because systemic inflammation and dyslipidemia are involved in the pathogenesis of atherosclerosis, Behcet's disease may play a part in the development of atherosclerosis. Lipid profile in Behcet's disease and the development of atherosclerosis remain to be controversial. In order to learn more abo...

Results: In conventional Doppler echocardiography, Mitral A-wave velocity and deceleration time were higher, and E/A ratio was lower in patients with BD (p=0.002, p=0.02, and p=0.006, respectively). Mitral E-wave velocity and isovolumetric relaxation time were comparable between groups (p>0.05). In TDI examination, E′/A′ ratio measured from lateral mitral annulus was lower, and A′ velocity meas...