Aging is associated with a progressive decline in physical and cognitive functions. The impact of age-dependent endocrine changes regulated by the central nervous system on the dynamics of neuronal behavior, neurodegeneration, cognition, biological rhythms, sexual behavior, and metabolism are reviewed. We also briefly review how functional deficits associated with increases in glucocorticoids a...

1. Adult male outbred albino mice were acutely injected with either of two dopamine (DA) agonists; Apomorphine, a receptor agonist, or Amantadine, a DA releasing agent. 2. Both drugs produced dose-related alterations in initial Y-maze behavior, consisting of significantly increased proportions of 2-arm entries. 3. This behavior has previously been shown to reflect an abnormal sttentional proces...

Imazethapyr is an herbicide that used in a variety of crops worldwide, including soybean and corn. The aim the present study was to evaluate biomarkers responses adult Leptodactylus latinasus exposed formulation Pivot® H (10.59% imazethapyr) laboratory at concentrations under conditions simulate two potential field exposure scenarios: immersion runoff (Scenario 1: 10 mg/L) direct droplets emitt...

This work studies the role of dispersing and dispersed phases in rheological properties fruit juices during concentration operations. A special focus was given to behavior phase (SS) when it is concentrated singly or simultaneously with (TSS). The experimental strategy consisted characterization viscoelastic flow various orange juice suspensions containing different concentrations soluble suspe...

Fourteen autopsied cases of malignant nephrosclerosis were classified into 6 of pure form in which syndrome of malignant hypertension developed from the beginning of the disease, and 8 of exacerbated form with appearance of the syndrome in the course of essential hypertension. Pathohistological study of these cases elucidated the differences in histologic manifestations between pure and exacerb...

Introduction Autistic children may have abnormal sensory perception, emotion dysregulation and behavior problems. The aim of this cross-sectional study was to explore the relationship between skin-mediated somatosensory signals emotion/behavior difficulties in autistic adolescents, comparison typically developing peers (TDP). Methods Thirty-eight adolescents 34 TDP completed a multidimensional ...

Lung cancer is classified into small-cell carcinoma (SCLC) and non-small-cell carcinoma (NSCLC). The profile of molecular and genetic alterations considerably differs between SCLC and NSCLC, as well as among the subtypes of NSCLC. Tp53 is inactivated in nearly 50% of NSCLC, while its mutations with functional inactivation are greatly prevalent in SCLC (70-100%). Rb gene alterations and protein ...

The involvement of dopamine in addiction has its origins in studies investigating reward and reinforced behavior in preclinical studies. Much of this research has been explored in the human brain using Positron Emission Tomography (PET) imaging of striatal dopamine transmission. These studies show that addiction is associated with a decrease in dopamine D2/3 receptors and a decrease in pre-syna...

BACKGROUND Studies have indicated that altered maternal micronutrients and vitamins influence the development of newborns and altered nutrient exposure throughout the lifetime may have potential health effects and increased susceptibility to chronic diseases. In recent years, folic acid (FA) exposure has significantly increased as a result of mandatory FA fortification and supplementation durin...