Introduction to bead modelling The size and detailed shape of rigid macromolecules or particles can be inferred from the properties of their solutions or suspensions. Some of these are hydrodynamic properties, such as the sedimentation coefficient, s, the translational diffusion coefficient, D,, rotational diffusion coefficients, D,, and relaxation times, z, and the intrinsic viscosity [q]. The...

original article   electrospun nanofibrous filter media have attracted considerable attention in the last decade. the present study aimed to develop the electrospun pan (polyacrylonitrile) filter media through experimental investigations for application in high-performance air filters. for this purpose, an experimental design was proposed to assess the effect of electrospinning process conditio...

We are developing a biosensor system, the Bead ARray Counter (BARC), based on the capture and detection of micron-sized, paramagnetic beads on a chip containing an array of giant magnetoresistive (GMR) sensors. Here we describe the design and performance of our current chip with 64 sensor zones, compare its performance with the previous chip design, and discuss a simple analytical model of the ...

In subcuticular wound closure, the use of anchorage beads or knots to maintain opposition of wound edges is a common practice, but can lead to complications. One hundred and one abdominal subcuticular wound closures (44 vertical and 57 transverse) were prospectively studied and assessment of wound swelling was made by measuring the length of exposed suture at both ends of the wound, on successi...

Antibody arrays have valuable applications in cancer research. Many different antibody array technologies have been developed, each with particular advantages, disadvantages, and optimal applications. The methods have been demonstrated on various sample types, such as serum, plasma, and other bodily fluids; cell culture supernatants; tissue culture lysates; and resected tumor specimens. The app...

A high-throughput and cost-effective single-nucleotide polymorphism (SNP) genotyping method based on a gold magnetic nanoparticle (GMNP) array with dual-color hybridization has been designed. Biotinylated single-strand polymerase chain reaction (PCR) products containing the SNP locus were captured by the GMNPs that were coated with streptavidin. The GMNP array was fabricated by immobilizing sin...

chitosan with excellent biodegradable and biocompatible characteristics has received attention as an oral drug delivery vehicle for controlled-release formulations. in this study an enteric-coated capsule containing theophylline-chitosan beads based on 23 factorial designs was prepared as a colon drug delivery system. the theophylline-chitosan gel beads were formulated by adding the drug-contai...

abstract in this study, the extraction of carotenoids from a new strain of yeast (sporobolomyces ruberrimus h110) by different chemical and physical methods was investigated. for chemical pretreatment methods, hcl at two different concentrations (0.2 and 0.5 n) and two different temperatures (55 and 75c), and dmso solvent (also at two different temperatures, 55 and 75c) were used. sonication an...